Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

What is a Nervous System?

What is a Nervous System?

The Sympathetic Nervous System

The Sympathetic Nervous System

The Parasympathetic Nervous System

The Parasympathetic Nervous System

The Central Dogma

The Central Dogma

Fixed Action Patterns

Fixed Action Patterns

A fixed action pattern (FAP) is a specific, hard-wired sequence of behaviors that occurs in response to an external stimulus, called a sign stimulus. The behavior is “fixed” because it is essentially unchangeable—proceeding similarly across individuals of a species every time it occurs.

Nervous System

Nervous System

The nervous system coordinates body functions through its complex network of nerve cells, enabling sensation and movement. It is divided into two primary parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is composed of the brain and the spinal cord. The brain acts as the body's control center, processing sensory information and coordinating responses. The spinal cord functions as a major signaling pathway for the brain and the rest of the body.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Translational Assessment of Omics Approaches in Endometriosis: Bridging Molecular Discovery with Clinical Utility.

International journal of molecular sciences·2026

Same author

Maternal obesity and inadequate gestational weight gain disrupts placental dopaminergic signaling: impact on infant neurodevelopment.

Frontiers in endocrinology·2026

Same author

Testosterone increases clonogenicity and self-renewal capacity of human glioblastoma cells.

The Journal of steroid biochemistry and molecular biology·2026

Same author

Testosterone-TGF-β crosstalk modulates cell migration in human glioblastoma-derived cell lines.

Steroids·2026

Same author

Hormonal regulation of androgen, estrogen receptor-α, and progesterone receptor expression in the adult male rabbit brain.

Hormones and behavior·2026

Same author

Placental serotonergic system dysregulation is associated with early impairments in infant neurodevelopment.

Frontiers in endocrinology·2026

Search research articles

Related Experiment Video

Updated: Jan 24, 2026

Electrophysiological Recording of The Central Nervous System Activity of Third-Instar Drosophila Melanogaster

Electrophysiological Recording of The Central Nervous System Activity of Third-Instar Drosophila Melanogaster

Published on: November 21, 2018

Progesterone Actions During Central Nervous System Development.

Juan Carlos González-Orozco¹, Ignacio Camacho-Arroyo¹

¹Unidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química, Universidad Nacional Autónoma de México, Mexico City, Mexico.

Frontiers in Neuroscience

|June 4, 2019

Summary

Progesterone, a steroid hormone, plays crucial roles beyond reproduction in the central nervous system (CNS). This review explores progesterone

Keywords:

brain sex differentiation brain tumors myelination neurodevelopment neuroprotection progesterone progesterone receptor

More Related Videos

Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY

Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY

Published on: June 30, 2016

Isolation of Mononuclear Cells from the Central Nervous System of Rats with EAE

Isolation of Mononuclear Cells from the Central Nervous System of Rats with EAE

Published on: December 4, 2007

Related Experiment Videos

Last Updated: Jan 24, 2026

Electrophysiological Recording of The Central Nervous System Activity of Third-Instar Drosophila Melanogaster

Electrophysiological Recording of The Central Nervous System Activity of Third-Instar Drosophila Melanogaster

Published on: November 21, 2018

Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY

Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY

Published on: June 30, 2016

Isolation of Mononuclear Cells from the Central Nervous System of Rats with EAE

Isolation of Mononuclear Cells from the Central Nervous System of Rats with EAE

Published on: December 4, 2007

Area of Science:

Neurobiology
Endocrinology
Developmental Neuroscience

Background:

Progesterone is traditionally linked to female reproductive functions.
Emerging evidence highlights its non-reproductive roles in the central nervous system (CNS) for both sexes.
Progesterone is synthesized within the brain by neurons and glial cells.

Purpose of the Study:

To review the diverse physiological actions of progesterone in the CNS.
To focus on the specific roles of progesterone during CNS development.

Main Methods:

This review synthesizes existing scientific literature on progesterone's CNS functions.
Analysis of studies investigating progesterone synthesis and action in neural tissues.

Main Results:

Progesterone regulates myelination, neuroprotection, neuromodulation, learning, memory, and mood.
It is involved in critical developmental processes like cell differentiation and neural circuit formation.
Increased progesterone synthesis occurs in the placenta and fetal brain during pregnancy.

Conclusions:

Progesterone is a key neurosteroid with significant implications for CNS development and function.
Its actions extend to fundamental neural processes, impacting brain health and development across both sexes.