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Spinal subarachnoid space tapering in patients with syringomyelia
Emily Rutan1, Neel Madan2, Ryan Zea3
12 Tufts University School of Medicine, Medstar Health, USA.
The Neuroradiology Journal
|June 5, 2019
Summary
Cervical spine tapering differs between patients with syringomyelia and controls. This study found significant differences in spinal canal diameter and dural sac cross-sectional area tapering, impacting cerebrospinal fluid dynamics.
Area of Science:
- Neurosurgery
- Radiology
- Spinal Anatomy
Background:
- Cervical spine tapering influences cerebrospinal fluid (CSF) dynamics.
- Reported differences in cervical spine taper ratios exist between syringomyelia patients and controls.
- Previous studies suggest variations in anteroposterior diameters impact CSF flow.
Purpose of the Study:
- To verify reported differences in cervical spine anteroposterior diameter tapering between syringomyelia patients and controls.
- To investigate differences in spinal canal cross-sectional area tapering.
- To correlate cervical spine morphology with syringomyelia.
Main Methods:
- Cervical spine MRI scans from syringomyelia (idiopathic or Chiari I) and control patients were analyzed.
- Anteroposterior diameters and cross-sectional areas of the spinal canal were measured at each cervical level.
- Taper ratios (C1-C4, C4-C7, C1-C7) were calculated and statistically compared using t-tests.
Main Results:
- Patients with Chiari I malformation and syringomyelia exhibited significantly steeper diameter-based taper ratios compared to controls.
- Dural sac cross-sectional areas demonstrated proportional tapering consistent with the diameter-based taper ratios across all groups.
- The study included 18 idiopathic syringomyelia, 28 Chiari I, and 29 control subjects.
Conclusions:
- Significant differences in cervical spine anteroposterior diameter tapering are present between syringomyelia patients and controls.
- Dural sac cross-sectional area tapering also differs significantly in patients with syringomyelia compared to controls.
- These morphological variations in cervical spine tapering may play a role in the pathophysiology of syringomyelia.
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