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Unexpected benefit from an 'old' metronomic chemotherapy regimen in advanced chordoma
Mariella Spalato Ceruso1, Andrea Napolitano1, Marianna Silletta1
1Medical Oncology, Universita Campus Bio-Medico di Roma, Roma, Lazio, Italy.
BMJ Case Reports
|June 5, 2019
Abstract:
In this case report, we describe an older adult man affected by advanced chordoma progressing after treatment with cisplatin and imatinib. The patient was symptomatic for uncontrolled pain. We decided to treat the patient with metronomic cyclophosphamide, unexpectedly achieving long-lasting clinical and radiological benefit.