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Predictors for Pediatric Blunt Cerebrovascular Injury (BCVI): An International Multicenter Analysis
Christian D Weber1, Rolf Lefering2, Matthias S Weber3
1Department of Orthopedics and Trauma Surgery, RWTH Aachen University Medical Center, Pauwels Street 30, 52074, Aachen, Germany. chrweber@ukaachen.de.
Insights
Blunt cerebrovascular injuries (BCVI) are rare in children but significantly increase mortality risk. Early recognition and management in high-risk pediatric trauma patients are crucial for better outcomes.
Area of Science:
- Trauma Surgery
- Pediatric Traumatology
- Vascular Surgery
Background:
- Blunt cerebrovascular injury (BCVI) guidelines exist for adults, but pediatric data are limited.
- BCVI is a severe injury pattern with potentially devastating consequences in children.
- Understanding pediatric BCVI is essential for improving patient outcomes.
Purpose of the Study:
- To characterize BCVI in the pediatric population.
- To analyze the prevalence, injury patterns, and outcomes of pediatric BCVI.
- To identify risk factors and predictors for BCVI in children.
Main Methods:
- International multicenter analysis of the TraumaRegister DGU® database (2002-2015).
- Inclusion of pediatric trauma patients (0-17 years) with Injury Severity Score (ISS) ≥ 9.
- Categorization of BCVI into carotid artery and vertebral artery injuries (VAI).
Main Results:
- 48 BCVIs identified in 42 children (0.5% prevalence) among 8128 pediatric trauma patients.
- Carotid injuries (0.4%) were more frequent than VAIs (0.1%).
- BCVI patients had higher rates of associated head, facial, chest, and spinal injuries, increased thromboembolic complications (8.3%), and excessive in-hospital mortality (38.1%).
Conclusions:
- BCVI is less common in pediatric than adult trauma patients but carries significant risks.
- Special attention to BCVI and its complications is warranted in the early management of severe pediatric trauma.
- High-risk children with severe trauma require vigilant screening for BCVI.
Introduction:
Practice guidelines for adult BCVI patients have been implemented recently, but data for this devastating injury pattern in children are still limited. An international multicenter analysis was performed to characterize BCVI in the pediatric population.
Methods:
The TraumaRegister DGU®, a prospectively maintained database, was analyzed (01/2002-12/2015). Pediatric patients (0-17 years) with major injuries [Injury Severity Score (ISS) ≥ 9 points] were included. BCVI was divided into carotid artery injury and vertebral artery injury (VAI). Data of demographics, injury, imaging, therapy, and outcome characteristics were analyzed with SPSS (Version 25, IBM Inc., Armonk, NY).
Results:
The study cohort included 8128 pediatric trauma patients. We identified 48 BCVIs in 42 children, resulting in an overall prevalence of 0.5%. Carotid injuries were diagnosed more frequently (n = 30; 0.4%) when compared to VAIs (n = 12; 0.1%). The coincidence of head (p = 0.028), facial (p ≤ 0.001), chest (p ≤ 0.001), and spinal injuries (p ≤ 0.001) was higher in BCVI patients. The risk for thromboembolic complications (8.3% vs. 1%, p = 0.026) and in-hospital mortality (38.1% vs. 7.7%, p ≤ 0.001) was excessive in children with BCVI. We identified various predictors for pediatric BCVI and quantified the cumulative impact of these risk factors.
Conclusion:
BCVI is more uncommon in pediatric than in adult trauma patients. Due to the considerable relevance of this injury for both children and adults, special attention should be paid to this entity and associated complications in the early treatment phase after severe pediatric trauma, especially in high-risk children.
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