Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Roles of Bacteria and Fungi in Plant Nutrition02:11

The Roles of Bacteria and Fungi in Plant Nutrition

47.2K
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
47.2K
Controlled-Potential Coulometry: Electrolytic Methods01:17

Controlled-Potential Coulometry: Electrolytic Methods

687
Controlled-potential coulometry, also known as potentiostatic coulometry, employs a three-electrode system in which the working electrode's potential is precisely regulated using a potentiostat. Platinum working electrodes are utilized for positive potentials, while mercury pool electrodes are favored for extremely negative potentials. The platinum counter electrode is separated from the analyte using a membrane or salt bridge to avoid interference in the analysis.
The chosen potential...
687
What is Genetic Engineering?00:49

What is Genetic Engineering?

79.8K
Overview
79.8K
Potential Energy00:52

Potential Energy

42.4K
The energy stored by a structure and location of matter in space is called potential energy. For instance, raising a kettlebell changes its spatial location and increases its potential energy. Similarly, a stretched rubber band contains potential energy which, under certain conditions, can be converted into other forms of energy, such as kinetic energy.
Chemical bonds that form attractive forces between atoms also contain potential energy, called chemical energy. When a chemical reaction...
42.4K
Role of Septins01:02

Role of Septins

2.1K
Septins are the recently discovered fourth major protein component of the cytoskeleton, along with microfilaments, microtubules, and intermediate filaments. These proteins can associate with other cytoskeletal filaments and carry out varied roles or can be free-floating in the cytoplasm.
Cellular Functions of Septins
Recent studies have revealed the multifaceted roles of septins in various cellular processes such as cytokinesis, ciliogenesis, and neurogenesis. Septins act as scaffolds and...
2.1K
The Role of Culture01:23

The Role of Culture

367
Culture plays a crucial role in shaping self-identity and influencing thought and behavior, a foundational interest within social psychology. The multicultural perspective recognizes that individuals do not exist in a vacuum; instead, their experiences, perceptions, and actions are deeply influenced by the intersecting dimensions of their cultural, ethnic, and social group affiliations.Cultural Influence on Self-Identity and Social PerceptionCultural frameworks inform how individuals define...
367

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of latent delay and environment infection on tuberculosis dynamics in a population.

Mathematical biosciences·2025
Same author

On final and peak sizes of an epidemic with latency and effect of behaviour change.

Journal of mathematical biology·2025
Same author

Modeling virus-stimulated proliferation of CD4<sup>+</sup> T-cell, cell-to-cell transmission and viral loss in HIV infection dynamics.

Mathematical biosciences·2024
Same author

Modelling the impact of precaution on disease dynamics and its evolution.

Journal of mathematical biology·2024
Same author

<math><msub><mi>R</mi> <mn>0</mn></msub></math> May Not Tell Us Everything: Transient Disease Dynamics of Some SIR Models Over Patchy Environments.

Bulletin of mathematical biology·2024
Same author

Population dynamics of a stoichiometric aquatic tri-trophic level model with fear effect.

Mathematical biosciences·2023

Related Experiment Video

Updated: Jan 23, 2026

Obtaining Hemocytes from the Hawaiian Bobtail Squid Euprymna scolopes and Observing their Adherence to Symbiotic and Non-Symbiotic Bacteria
05:29

Obtaining Hemocytes from the Hawaiian Bobtail Squid Euprymna scolopes and Observing their Adherence to Symbiotic and Non-Symbiotic Bacteria

Published on: February 11, 2010

13.6K

Modeling the Potential Role of Engineered Symbiotic Bacteria in Malaria Control.

Xiunan Wang1, Xingfu Zou2

  • 1Department of Mathematical and Statistical Sciences, University of Alberta, Edmonton, AB, T6G 2G1, Canada. xiunan@ualberta.ca.

Bulletin of Mathematical Biology
|June 5, 2019
PubMed
Summary

Engineered bacteria Serratia AS1 show promise for malaria biocontrol by inhibiting parasite development in mosquitoes. Mathematical modeling suggests long-term investment and integrated strategies are crucial for malaria elimination.

Keywords:
Basic reproduction numberEngineered bacteriaGlobal attractivityMalaria modelSerratia AS1

More Related Videos

Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive
10:21

Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive

Published on: July 4, 2007

11.1K
Engineering Adherent Bacteria by Creating a Single Synthetic Curli Operon
15:28

Engineering Adherent Bacteria by Creating a Single Synthetic Curli Operon

Published on: November 16, 2012

15.0K

Related Experiment Videos

Last Updated: Jan 23, 2026

Obtaining Hemocytes from the Hawaiian Bobtail Squid Euprymna scolopes and Observing their Adherence to Symbiotic and Non-Symbiotic Bacteria
05:29

Obtaining Hemocytes from the Hawaiian Bobtail Squid Euprymna scolopes and Observing their Adherence to Symbiotic and Non-Symbiotic Bacteria

Published on: February 11, 2010

13.6K
Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive
10:21

Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive

Published on: July 4, 2007

11.1K
Engineering Adherent Bacteria by Creating a Single Synthetic Curli Operon
15:28

Engineering Adherent Bacteria by Creating a Single Synthetic Curli Operon

Published on: November 16, 2012

15.0K

Area of Science:

  • Vector-borne disease control
  • Microbial biocontrol agents
  • Mathematical epidemiology

Background:

  • Malaria remains a significant global health burden, necessitating novel control strategies.
  • Engineered symbiotic bacteria, such as Serratia AS1, demonstrate potential for sustainable malaria biocontrol.
  • Previous research indicates rapid dissemination and parasite inhibition by Serratia AS1 in laboratory settings.

Purpose of the Study:

  • To develop a climate-based mathematical model for malaria transmission incorporating engineered Serratia AS1 bacteria.
  • To analyze the dynamics of the disease-free and endemic states based on key reproduction ratios.
  • To evaluate the long-term efficacy of Serratia AS1 for malaria elimination in a specific field context.

Main Methods:

  • Development of a mathematical model simulating vertical and horizontal transmission of Serratia AS1 in mosquito populations.
  • Analysis of model dynamics based on the vector reproduction ratio (R_v) and basic reproduction ratio (R_0).
  • Numerical simulations and a case study in Douala, Cameroon, to assess field implementation effects.

Main Results:

  • Model dynamics are critically dependent on R_v and R_0.
  • Specific thresholds of R_v and R_0 determine the global attractiveness of mosquito-free, disease-free periodic, or positive periodic solutions.
  • Numerical analysis indicates that Serratia AS1 alone may require at least 25 years for malaria elimination in Douala.

Conclusions:

  • The study confirms the potential of Serratia AS1 as a biocontrol agent for malaria.
  • Achieving malaria elimination necessitates sustained, long-term investment and integrated control measures.
  • Mathematical modeling provides valuable insights into the deployment strategies for novel biocontrol agents.