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Updated: Jan 23, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
Finding of Hyperostosis Frontalis Interna During the Autopsy Procedure: Forensic Issues
Agathe Bascou1, Frederic Savall1, Marion Vergnault1
1Service de médecine légale, Centre Hospitalier Universitaire Rangueil, Avenue du Professeur Jean Poulhès, 31059, Toulouse Cedex 9, France.
Hyperostosis frontalis interna, a skull bone thickening, is examined in three medicolegal autopsies. This condition, linked to metabolic and psychiatric issues in Morgagni-Stewart-Morel syndrome, has forensic implications for aging and sexing skeletons.
Area of Science:
- Forensic Pathology
- Neuropathology
- Endocrinology
Background:
- Hyperostosis frontalis interna (HFI) is a common cranial bone thickening.
- Its clinical significance has been historically debated, potentially being currently underestimated.
- HFI is associated with metabolic and endocrine disorders and neuropsychiatric symptoms.
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