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High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses
Published on: May 5, 2014
Recent advances in broad-spectrum resistance to the rice blast disease
Weitao Li1, Mawsheng Chern2, Junjie Yin1
1State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China (In preparation), State Key Laboratory of Hybrid Rice, Key Laboratory of Major Crop Diseases & Collaborative Innovation Center for Hybrid Rice in Yangtze River Basin, Rice Research Institute, Sichuan Agricultural University at Wenjiang, Chengdu, Sichuan 611130, China.
Abstract:
Blast is arguably the most devastating fungal disease of rice. Systematic studies of this disease have made significant progress and identified many genes. Broad-spectrum resistance is highly preferred in agricultural practice. Here, we focus our discussion on resistance (R) and defense-regulator (DR) genes that confer broad-spectrum resistance to Magnaporthe oryzae, in particular those potentially causing no significant yield penalties. Recent advances show that broad-spectrum resistance can be achieved without significant yield penalties, or even with yield benefits. Cross talks of defense signaling mediated by these genes are present that may allow the host to integrate different anti-fungal factors against M. oryzae infection. We also summarize possible mechanisms underlying broad-spectrum resistance to rice blast.
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