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Updated: Jan 23, 2026

Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
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Plant-derived drugs and their applicaction in the anticancer therapy

Romana Blažejová, Jan Hošek

    Ceska a Slovenska Farmacie : Casopis Ceske Farmaceuticke Spolecnosti a Slovenske Farmaceuticke Spolecnosti
    |June 6, 2019
    PubMed

    Insights

    Natural products offer promising alternatives to synthetic chemotherapy for cancer treatment. This review highlights anticancer drugs derived from nature currently in clinical trials or use.

    Area of Science:

    • Pharmacology
    • Natural Product Chemistry
    • Oncology

    Background:

    • Synthetic chemotherapeutics for cancer treatment cause significant side effects and resistance.
    • There is a critical need for novel anticancer agents with improved safety profiles.
    • Natural products represent a rich source of diverse chemical structures with therapeutic potential.

    Purpose of the Study:

    • To review anticancer drugs (cytostatics) inspired by natural products.
    • To highlight agents that are either in clinical trials or already in established use.
    • To underscore the importance of natural product-derived compounds in oncology.

    Main Methods:

    • Literature review of scientific databases.
    • Identification of natural product-inspired cytostatics.
    • Analysis of their clinical trial status and therapeutic application.

    Main Results:

    • Several natural product-inspired compounds are progressing through clinical trials.
    • Some natural product derivatives have been successfully integrated into cancer therapy.
    • These agents demonstrate diverse mechanisms of action against various cancers.

    Conclusions:

    • Natural products are a valuable resource for developing new anticancer drugs.
    • Nature-inspired cytostatics offer potential advantages over traditional synthetic agents.
    • Further research into natural product-derived compounds is crucial for advancing cancer treatment.
    Keywords:
    clinical trialscytostaticsnatural compoundstumour

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