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Japan promotes cancer genomic medicine through a network of leading Designated Core Hospitals and regional Cooperative Hospitals. Collaboration, including molecular tumor boards (Expert Panels), is crucial for advancing genomic-based cancer care.

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Area of Science:

  • Oncology
  • Genomics
  • Healthcare Systems

Background:

  • Japan is implementing cancer genomic medicine via a tiered network of Designated Core Hospitals and Cooperative Hospitals.
  • Molecular tumor boards, termed "Expert Panels," are central to interpreting genomic data and guiding treatment decisions.
  • Effective cancer genomic medicine relies on interinstitutional collaboration and robust data management.

Purpose of the Study:

  • To outline the collaborative framework for cancer genomic medicine in Japan.
  • To highlight the role of Expert Panels in clinical decision-making.
  • To identify key areas requiring cooperation between different levels of healthcare institutions.

Main Methods:

  • Describing the designated roles of "Designated Core Hospitals for Cancer Genomic Medicine" and "Cooperative Hospitals for Cancer Genomic Medicine."
  • Explaining the function and necessity of "Expert Panels" for treatment recommendations.
  • Identifying collaborative tasks including data registration (C-CAT), managing genomic testing, and workforce development.

Main Results:

  • Eleven Designated Core Hospitals and 135 Cooperative Hospitals are actively engaged.
  • Expert Panels, led by Core Hospitals with Cooperative Hospital participation, are essential for genomic medicine.
  • A well-managed web system can facilitate Expert Panel operations and information sharing.

Conclusions:

  • Interinstitutional collaboration is vital for the widespread adoption of cancer genomic medicine in Japan.
  • Streamlining data sharing and resource management through cooperation is necessary.
  • Continued encouragement of collaboration will accelerate the integration of genomic insights into cancer care.