Related Experiment Video
Updated: Jan 23, 2026

Models of Bone Metastasis
Published on: September 4, 2012
[Efficacy of 89Sr as Pain Relief for Gastric Cancer Bone Metastasis]
Itsuki Koganezawa1, So Katayanagi, Kei Yokozuka
1Dept. of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center.
Abstract:
We experienced 2 cases in which strontium chloride was used for pain associated with gastric cancer bone metastasis. Case 1 was of a 69-year-old woman. In 2015, she underwent surgery for advanced gastric cancer followed by adjuvant chemotherapy with S-1 for 1 year. Multiple bone metastases were confirmed 2 years and 3 months after surgery. Obvious pain relief was obtained after 89Sr was administered, and SOX therapy was started. Case 2 was of a 62-year-old man. In 2016, he underwent curative surgery for stomach cancer. Chemotherapy with S-1 was performed for approximately 6 months, but 9 months after surgery multiple LN metastases, liver metastasis, and multiple bone metastases were observed . In case 2, 89Sr was administered, but good pain control was not obtained. The use of 89Sr for pain relief against multiple bone metastases should be based on the previous literature.
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