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Chronic consumption of ethanol increases glucose oxidation in isolated cerebral tissue of rat
E Ruczkal-Pietrzak1, P A Wilce, B C Shanley
1Department of Biochemistry, University of Queensland, St. Lucia, Australia.
Neuroscience Letters
|September 11, 1987
Abstract:
Tolerance to ethanol was induced in male Wistar rats by adding 15% ethanol to the drinking water for 3 and 9 months. The oxidation of [U-14C]glucose was measured in cerebral cortex prisms. 14CO2 production in prisms for ethanol-treated animals was markedly increased when compared to controls. Neither a single injection of a low dose of ethanol nor a comparable concentration of ethanol in vitro had this stimulatory effect.