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Related Experiment Videos

Premedication with lorazepam for bronchoscopy under general anaesthesia.

J M Hewitt, A M Barr

    British Journal of Anaesthesia
    |November 1, 1978
    PubMed
    Summary

    Lorazepam effectively sedated anxious patients before bronchoscopy, improving cooperation and reducing recall of the procedure. Dosing adjustments are recommended for optimal patient outcomes.

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    Area of Science:

    • Anesthesiology
    • Pharmacology

    Background:

    • Bronchoscopy requires effective patient sedation and anxiolysis.
    • Previous premedication agents like pethidine and diazepam have limitations.

    Purpose of the Study:

    • To evaluate lorazepam as a premedication agent for bronchoscopy.
    • To assess lorazepam's efficacy as a night sedative and its impact on patient recall and cooperation.

    Main Methods:

    • 100 patients received intramuscular lorazepam before bronchoscopy under general anesthesia.
    • 49 anxious patients also received oral lorazepam for preoperative night sedation.
    • Patient recall and cooperation were assessed post-administration.

    Main Results:

    • Lorazepam demonstrated effective night sedation in 42 out of 49 patients.
    • 64% of patients experienced complete amnesia for 4-10 hours post-injection.
    • Minimal side-effects and impressive patient acceptance were noted, with one case of awareness.

    Conclusions:

    • Lorazepam is an effective premedication for bronchoscopy, offering advantages over pethidine and diazepam.
    • Further research is needed to optimize lorazepam dosage based on patient factors like weight, age, sex, and alcohol intake.
    • Lorazepam significantly reduces recall and improves patient cooperation during bronchoscopy.

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