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Updated: Jan 23, 2026

Metacarpal Small Incision for Carpal Tunnel Syndrome
Published on: April 5, 2024
[Pyoderma gangrenosum: a complication following surgery for carpal tunnel syndrome]
Daan Geerards1, Thijs de Wit1, Guido H C G Dolmans1,2
1Amphia Ziekenhuis, afd. Plastische Chirurgie, Breda.
Background:
Pyoderma gangrenosum is a rare condition with an unpredictable disease course. The condition is accompanied by tissue decay and recognition often comes late. Pyoderma gangrenosum has clinical features similar to an infection, but does not react to antibiotics. The condition can develop following a surgical procedure or can be worsened by one. To date, only one other case of pyoderma gangrenosum following surgery for carpal tunnel syndrome has been described in the literature.
Case Description:
A 60-year-old man developed painful ulcers shortly after surgery for carpal tunnel syndrome, a clinical picture representing a serious infection. Antibiotics and surgical debridement did not lead to improvement. Cultures from the wound did not contain micro-organisms. Following histological investigation a diagnosis of pyoderma gangrenosum was made. Administration of a high dosage of prednisone led to a swift improvement and the wound healed.
Conclusion:
Timely recognition of pyoderma gangrenosum is essential to prevent unnecessary surgical treatment and worsening of the condition. Systemic glucocorticoids are the treatment of first choice for pyoderma gangrenosum.
Insights
Pyoderma gangrenosum is a rare, ulcerative skin condition that can mimic infection. Prompt diagnosis and treatment with systemic glucocorticoids are crucial for healing and preventing complications.
Area of Science:
- Dermatology
- Surgical Pathology
Background:
- Pyoderma gangrenosum (PG) is a rare inflammatory ulcerative condition with an unpredictable course.
- It presents with tissue decay, often mimicking infection but unresponsive to antibiotics.
- PG can be triggered or exacerbated by surgical procedures.
Observation:
- A 60-year-old male developed painful ulcers post-carpal tunnel surgery.
- Initial treatment with antibiotics and debridement failed; wound cultures were negative.
- Histological examination confirmed pyoderma gangrenosum.
Findings:
- High-dose prednisone administration resulted in rapid improvement and wound healing.
- This case highlights a rare instance of PG following carpal tunnel surgery.
Implications:
- Early recognition of pyoderma gangrenosum is vital to avoid misdiagnosis and inappropriate surgical interventions.
- Systemic glucocorticoids represent the primary treatment modality for this condition.
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