Intrageneric and Intergeneric Interactions Developed by Oral Streptococci: Pivotal Role in the Pathogenesis of Oral Diseases
Yandi Chen1, Yuqing Li1, Jing Zou1
1State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China.
Abstract:
Oral streptococci are among the most abundant genera present in the oral cavity. They are usually the first colonizers of oral surfaces and they develop extensive microbial interactions, playing a fundamental role in the pathogenesis of oral diseases such as dental caries and periodontitis. In addition to physical adherence, streptococcal cells also exchange messages with cells from another Streptococcus spp. and other microorganisms in the form of metabolites and signaling molecules. In this review, we focused on these intrageneric and intergeneric interactions, and their association with oral diseases.
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