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Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence

Lori A Daiello1, Annie M Racine, Ray Yun Gou

  • 1From the Alzheimer's Disease and Memory Disorders Center, Rhode Island Hospital, Providence, Rhode Island (L.A.D.) Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts (A.M.R., R.Y.G., S.K.I.) Harvard Medical School, Boston, Massachusetts (A.M.R., E.R.M., Z.X., L.J.K., K.V.V., S.K.I.) Departments of Medicine (E.R.M., S.K.I.) Anesthesia and Critical Care (L.J.K.), Beth Israel Deaconess Medical Center, Boston, Massachusetts Department of Anesthesia, Massachusetts General Hospital, Boston, Massachusetts (Z.X.) Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Boston, Massachusetts (K.V.V.) Departments of Psychiatry and Human Behavior (R.N.J.) Neurology (L.A.D., R.N.J.), Brown University Warren Alpert Medical School, Providence, Rhode Island.

Anesthesiology
|June 6, 2019
PubMed
Summary

Postoperative delirium increases the risk of postoperative cognitive dysfunction within the first month after surgery. However, this association diminishes over longer follow-up periods, suggesting distinct neurocognitive deficits.

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