Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

387
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
387
Divergence and Curl01:15

Divergence and Curl

3.1K
The divergence of a vector field at a point is the net outward flow of the flux out of a small volume through a closed surface enclosing the volume, as the volume tends to zero. More practically, divergence measures how much a vector field spreads out or diverges from a given point. For an outgoing flux, conventionally, the divergence is positive. The diverging point is often called the "source" of the field. Meanwhile, the negative divergence of a vector field at a point means that the vector...
3.1K
Divergence and Stokes' Theorems01:06

Divergence and Stokes' Theorems

3.6K
The divergence and Stokes' theorems are a variation of Green's theorem in a higher dimension. They are also a generalization of the fundamental theorem of calculus. The divergence theorem and Stokes' theorem are in a way similar to each other; The divergence theorem relates to the dot product of a vector, while Stokes' theorem relates to the curl of a vector. Many applications in physics and engineering make use of the divergence and Stokes' theorems, enabling us to write...
3.6K
Gene Duplication and Divergence02:37

Gene Duplication and Divergence

7.9K
The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
7.9K
¹H NMR: Interpreting Distorted and Overlapping Signals01:02

¹H NMR: Interpreting Distorted and Overlapping Signals

1.5K
Spin systems where the difference in chemical shifts of the coupled nuclei is greater than ten times J are called first-order spin systems. These nuclei are weakly coupled, and their chemical shifts and coupling constant can generally be estimated from the well-separated signals in the spectrum.
As Δν decreases and the signals move closer, the doublets appear increasingly distorted. The intensities of the inner lines increase at the cost of those of the outer lines as the signals are...
1.5K
Cognitive Dissonance01:38

Cognitive Dissonance

36.8K
Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
36.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A systematic review and meta-analysis of the relationship between midlife physical activity and later-life cognition: Is sex an overlooked factor?

Frontiers in neuroendocrinology·2026
Same author

Composite scores to detect and monitor cognitive dysfunction in preclinical and prodromal Alzheimer's disease: A narrative review.

Journal of Alzheimer's disease : JAD·2026
Same author

Contingency of Plasma Dementia Biomarkers on Cognitive Profiles for Prognosis of Incident Dementia: The ARIC Study.

Neurology·2026
Same author

Changes in Housework Frequency and Subsequent Cognitive Function and Rate of Decline Among Adults Aged ≥ 65 in the United States, 2008-2018.

The Permanente journal·2025
Same author

Diabetes and cognitive health in India: a nationally representative survey of adults aged 45 years and older.

BMJ open·2025
Same author

Dementia ascertainment in India and development of nation-specific cutoffs: A machine learning and diagnostic analysis.

Alzheimer's & dementia (Amsterdam, Netherlands)·2025

Related Experiment Video

Updated: Jan 23, 2026

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration
08:17

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration

Published on: February 27, 2018

17.0K

Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence.

Lori A Daiello1, Annie M Racine, Ray Yun Gou

  • 1From the Alzheimer's Disease and Memory Disorders Center, Rhode Island Hospital, Providence, Rhode Island (L.A.D.) Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts (A.M.R., R.Y.G., S.K.I.) Harvard Medical School, Boston, Massachusetts (A.M.R., E.R.M., Z.X., L.J.K., K.V.V., S.K.I.) Departments of Medicine (E.R.M., S.K.I.) Anesthesia and Critical Care (L.J.K.), Beth Israel Deaconess Medical Center, Boston, Massachusetts Department of Anesthesia, Massachusetts General Hospital, Boston, Massachusetts (Z.X.) Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Boston, Massachusetts (K.V.V.) Departments of Psychiatry and Human Behavior (R.N.J.) Neurology (L.A.D., R.N.J.), Brown University Warren Alpert Medical School, Providence, Rhode Island.

Anesthesiology
|June 6, 2019
PubMed
Summary

Postoperative delirium increases the risk of postoperative cognitive dysfunction within the first month after surgery. However, this association diminishes over longer follow-up periods, suggesting distinct neurocognitive deficits.

More Related Videos

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

6.9K
Postoperative Ileus Murine Model
04:26

Postoperative Ileus Murine Model

Published on: July 12, 2024

1.3K

Related Experiment Videos

Last Updated: Jan 23, 2026

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration
08:17

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration

Published on: February 27, 2018

17.0K
A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

6.9K
Postoperative Ileus Murine Model
04:26

Postoperative Ileus Murine Model

Published on: July 12, 2024

1.3K

Area of Science:

  • Neuroscience
  • Geriatric Medicine
  • Anesthesiology

Background:

  • Postoperative delirium and postoperative cognitive dysfunction share risk factors but their relationship is unclear.
  • Understanding this relationship is crucial for managing perioperative neurocognitive disorders.

Purpose of the Study:

  • To determine the prevalence of postoperative cognitive dysfunction.
  • To investigate the association between in-hospital delirium and postoperative cognitive dysfunction.

Main Methods:

  • Observational study using data from the Successful Aging after Elective Surgery study.
  • Delirium assessed daily using Confusion Assessment Method; cognitive dysfunction evaluated using International Study of Postoperative Cognitive Dysfunction criteria.
  • Associations examined at 1, 2, and 6 months post-surgery.

Main Results:

  • 24% of participants developed delirium; 47% experienced cognitive dysfunction at 1 month, decreasing over time.
  • Poor agreement and small correlations observed between delirium and cognitive dysfunction.
  • Delirium elevated the risk of cognitive dysfunction at 1 month (RR=1.34) but not at 2 or 6 months.

Conclusions:

  • Delirium significantly increases short-term postoperative cognitive dysfunction risk.
  • The association between delirium and cognitive dysfunction is not sustained long-term.
  • Postoperative delirium and cognitive dysfunction may represent distinct perioperative neurocognitive deficits.