Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

541
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
541
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

2.3K
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
2.3K
Identifying Statistically Significant Differences: The F-Test01:14

Identifying Statistically Significant Differences: The F-Test

3.3K
The F-test is used to compare two sample variances to each other or compare the sample variance to the population variance. It is used to decide whether an indeterminate error can explain the difference in their values. The underlying assumptions that allow the use of the F-test include the data set or sets are normally distributed, and the data sets are independent of each other. The test statistic F is calculated by dividing one variance by another. In other words, the square of one standard...
3.3K
Case Studies01:22

Case Studies

13.4K
There are many research methods available to psychologists in their efforts to understand, describe, and explain behavior and the cognitive and biological processes that underlie it.
13.4K
Design Example: Identifying the Locations of Monuments in the Field Using Global Positioning System Device01:30

Design Example: Identifying the Locations of Monuments in the Field Using Global Positioning System Device

389
Surveyors use Global Positioning System (GPS) technology to measure the precise location and elevation of points on Earth. In a recent survey, GPS receivers were used to determine the coordinates and elevations of two park monuments. The process involved careful mission planning, data collection, and correction to ensure accuracy. The survey began with mission planning to identify optimal satellite visibility and minimize Position Dilution of Precision (PDOP). A geodetic control point...
389
Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

299
Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
299

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Developing an Intervention Framework to Prevent Surgical Complications in Patients With Metabolic Syndrome: A Qualitative Study of Health Professional Perspectives on Barriers and Enablers.

ANZ journal of surgery·2026
Same author

The 12-node rule in irradiated rectal cancer: time for reappraisal?

Journal of gastrointestinal oncology·2026
Same author

The Economic Burden of Metabolic Syndrome in Elective Surgery: An Australian Cost-of-Illness Study.

ANZ journal of surgery·2026
Same author

Optimising Colorectal Cancer Care in Western Australia: Surveillance and Recurrence Insights.

ANZ journal of surgery·2026
Same author

Utility of Single Transhiatal Chest Drainage After Minimally Invasive Esophagectomy: A Propensity-Score Matched Study of Safety and Feasibility.

ANZ journal of surgery·2025
Same author

Guanine is an inhibitor of c-jun terminal kinases.

Scientific reports·2025

Related Experiment Video

Updated: Jan 23, 2026

Principles of Rodent Surgery for the New Surgeon
10:29

Principles of Rodent Surgery for the New Surgeon

Published on: January 6, 2011

117.1K

Can Surgeons Identify Appendicitis Macroscopically? Results From a Multicentre Prospective Study.

Da Wei Thong1, Stephen Crouch1, Samuel Morgan2

  • 1Department of General Surgery, Gold Coast University Hospital.

Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
|June 6, 2019
PubMed
Summary

Intraoperative macroscopic diagnosis of appendicitis is inaccurate, with a 22.4% false-negative rate. Consultant surgeons showed the lowest false-negative rates, indicating experience improves diagnostic accuracy.

More Related Videos

An Analog Macroscopic Technique for Studying Molecular Hydrodynamic Processes in Dense Gases and Liquids
11:03

An Analog Macroscopic Technique for Studying Molecular Hydrodynamic Processes in Dense Gases and Liquids

Published on: December 4, 2017

9.0K
A Technique to Functionalize and Self-assemble Macroscopic Nanoparticle-ligand Monolayer Films onto Template-free Substrates
08:09

A Technique to Functionalize and Self-assemble Macroscopic Nanoparticle-ligand Monolayer Films onto Template-free Substrates

Published on: May 9, 2014

11.4K

Related Experiment Videos

Last Updated: Jan 23, 2026

Principles of Rodent Surgery for the New Surgeon
10:29

Principles of Rodent Surgery for the New Surgeon

Published on: January 6, 2011

117.1K
An Analog Macroscopic Technique for Studying Molecular Hydrodynamic Processes in Dense Gases and Liquids
11:03

An Analog Macroscopic Technique for Studying Molecular Hydrodynamic Processes in Dense Gases and Liquids

Published on: December 4, 2017

9.0K
A Technique to Functionalize and Self-assemble Macroscopic Nanoparticle-ligand Monolayer Films onto Template-free Substrates
08:09

A Technique to Functionalize and Self-assemble Macroscopic Nanoparticle-ligand Monolayer Films onto Template-free Substrates

Published on: May 9, 2014

11.4K

Area of Science:

  • Surgical pathology
  • Diagnostic accuracy
  • Appendicitis management

Background:

  • Accurate intraoperative diagnosis of appendicitis is crucial for patient management.
  • Macroscopic assessment by surgeons is a key component of this diagnosis.

Purpose of the Study:

  • To evaluate the accuracy of intraoperative macroscopic diagnosis of appendicitis compared to histopathology.
  • To identify factors predicting discrepancies between macroscopic and histopathologic findings.

Main Methods:

  • A multicenter, prospective, observational study involving 1169 patients undergoing appendectomy.
  • Data collected included macroscopic diagnosis, histopathologic results, surgeon seniority, and preoperative imaging.

Main Results:

  • The overall false-negative (FN) rate was 22.4%, and the false-positive (FP) rate was 8.2%.
  • Surgeon seniority did not significantly impact diagnostic accuracy (P=0.069), but consultant surgeons had the lowest FN rate (15.6%).
  • Female patients and preoperative ultrasound increased FN odds, while preoperative CT scans decreased them.

Conclusions:

  • Intraoperative macroscopic identification of appendicitis is unreliable, with a significant FN rate of 22.4%.
  • Factors like surgeon experience and preoperative imaging influence diagnostic accuracy, highlighting areas for potential improvement.