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Ontology-Based Interactive Visualization of Patient-Generated Research Questions

David Borland1, Laura Christopherson1, Charles Schmitt2

  • 1RENCI, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States.

Applied Clinical Informatics
|June 6, 2019
PubMed

Insights

Researchers can now better explore patient-suggested research topics for Crohn's disease and colitis. An interactive tool and ontology help identify and prioritize research agendas from patient discussions.

Area of Science:

  • Medical Informatics
  • Patient-Reported Outcomes
  • Ontology Engineering

Background:

  • Crohn's disease and colitis significantly impact patients' quality of life, necessitating effective disease management strategies.
  • The Crohn's and Colitis Foundation-IBD Partners at UNC-Chapel Hill developed an interactive website with a forum for patient experiences and research suggestions.

Purpose of the Study:

  • To enhance researchers' ability to navigate and analyze patient-generated research topics from online discussion forums.
  • To facilitate the identification of key research themes, their scope, and interconnections for prioritizing research agendas.

Main Methods:

  • Developed a domain-specific ontology to structure themes within the patient discussion forum.
  • Created a prototype interactive visualization tool integrating the ontology with forum content for linked data exploration.

Main Results:

  • The visualization tool offers linked views of the ontology, clustered research topics, and detailed forum discussions.
  • Demonstrated an example scenario of researchers utilizing the tool to identify and analyze patient-suggested research.

Conclusions:

  • Integrating a community-specific ontology with interactive visualization tools offers a powerful method for analyzing user-generated research questions.
  • This approach aids researchers in more effectively understanding and prioritizing research agendas based on patient input.
Abstract

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