Related Experiment Video
Updated: Jan 23, 2026

Imaging the Human Immunological Synapse
Published on: December 26, 2019
Cascade of immunologic adverse events related to pembrolizumab treatment
Arnaud Dhenin1, Vassiliki Samartzi2, Sarah Lejeune1
1Department of Medical Oncology, Hopital de Jolimont, Haine-Saint-Paul, Belgium.
Abstract:
Immune checkpoint inhibitors, such as pembrolizumab, have significantly improved cancer patient outcome. Toxicities are usually moderate and manageable. However, some adverse events, if not early recognised, could be life-threatening. We report a patient with non-small cell lung cancer who received treatment with pembrolizumab and developed multiple immune-related adverse events both during and after completing treatment, including rash, pericarditis, colitis and myasthenia gravis.
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