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Related Concept Videos

What are Cells?01:07

What are Cells?

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Cells are the smallest and basic units of life, whether it is a single cell that forms the entire organism, e.g., in a bacterium or trillions of them, e.g., in humans. No matter what organism a cell is a part of, they share specific characteristics.
Basic Characteristics of Cells
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Cells are the smallest and basic units of life, whether it is a single cell that forms the entire organism, e.g., in a bacterium, or trillions of them, e.g., in humans. No matter what organism a cell is a part of, they share specific characteristics.
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A concentration cell is a type of a  voltaic cell constructed by connecting two almost identical half-cells, both based on the same half-reaction and using the same electrode, differing only in the concentration of one redox species. A concentration cell's potential, therefore, is determined only by the concentration difference of the particular redox species.
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Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.
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Related Experiment Video

Updated: Jan 23, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

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[B-cell lymphomas].

Daisuke Ennishi1

  • 1Department of Hematology and Oncology, Okayama University Hospital.

[Rinsho Ketsueki] the Japanese Journal of Clinical Hematology
|June 7, 2019
PubMed
Summary

Genetic abnormalities in B-cell lymphomas (BLs) are key to understanding diverse disease subtypes like diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL). Identifying these genetic features aids in patient stratification and developing targeted therapies.

Area of Science:

  • Hematologic Oncology
  • Molecular Pathology
  • Genetics

Background:

  • B-cell lymphomas (BLs) are diverse hematologic tumors classified by the WHO.
  • Tumorigenesis in lymphoid malignancies is linked to various molecular genetic abnormalities.
  • Advances in genetic analysis reveal novel and recurrent genetic abnormalities in BLs.

Purpose of the Study:

  • To describe patient-stratification possibilities based on genetic abnormalities in diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL).
  • To introduce genetic features and clinical importance of BL and mantle cell lymphoma (MCL) in Japanese patients.

Main Methods:

  • Utilizing molecular pathology techniques to identify genetic abnormalities.
  • Analyzing genetic features associated with DLBCL, FL, and MCL.
Keywords:
B-cell lymphomaClinical relevanceGeneticsPrecision medicine

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  • Reviewing recent advances in genetic analysis technology for lymphoid malignancies.

    • Main Results:

    • Discovery of novel and recurrent genetic abnormalities in lymphoid tumorigenesis.
    • Identification of genetic alterations crucial for DLBCL and FL.
    • Characterization of genetic features in BL and MCL impacting clinical importance.

    Conclusions:

    • Genetic abnormalities are pivotal for classifying and understanding BLs.
    • Molecular pathology techniques are essential for identifying key genetic alterations.
    • Understanding genetic features facilitates patient stratification and therapeutic development for lymphomas.