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Updated: Jan 23, 2026

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
Identification of separated lenticular planes using optical coherence tomography
Ke Zheng1,2,3, Tian Han1,2,3, Feng Zhao1,2,3
1NHC Key Laboratory of Myopia, Fudan University, Shanghai, China; Laboratory of Myopia, Chinese Academy of Medical Sciences, Beijing, China.
Optical coherence tomography (OCT) helps surgeons identify separated lenticular planes during small incision lenticule extraction (SMILE). This imaging technique visualizes distinct layers, aiding in accurate lenticule removal and confirming successful separation post-procedure.
Area of Science:
- Ophthalmology
- Medical Imaging
- Surgical Technology
Background:
- Small incision lenticule extraction (SMILE) is a refractive surgery technique.
- Accurate separation of lenticular planes is crucial for successful SMILE outcomes.
- Identifying these planes can be challenging during the procedure.
Purpose of the Study:
- To evaluate the utility of anterior segment optical coherence tomography (AS-OCT) in identifying separated lenticular planes during SMILE.
- To demonstrate how AS-OCT can visualize the distinct planes created during the SMILE procedure.
Main Methods:
- AS-OCT was used to examine eyes before and after lenticule separation in SMILE procedures.
- Brightness scores of anterior and posterior lenticular planes were compared after manual separation.
- AS-OCT imaging was performed immediately after laser scan, after plane separation, and post-extraction.
Main Results:
- AS-OCT revealed two bright lines post-laser scan, indicating distinct planes.
- The separated plane consistently showed less brightness compared to the unseparated plane (P < 0.001).
- A smooth hyperreflective line was observed between the cap and stromal bed post-extraction, persisting for 24 hours.
Conclusions:
- AS-OCT is effective in identifying separated lenticular planes during SMILE.
- Manual separation largely resolves bubbles, and AS-OCT confirms successful plane separation.
- This imaging modality can enhance surgical precision and outcomes in SMILE.
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