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Updated: Jan 23, 2026

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice
Published on: June 29, 2018
Leaving the Lights on Using Gamma Entrainment to Protect against Neurodegeneration
Ana Catarina Ferreira1, Joseph M Castellano1
1Nash Family Department of Neuroscience, Ronald M. Loeb Center for Alzheimer's Disease, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 1425 Madison Ave., New York, NY 10029, USA.
Abstract:
The brain generates natural oscillations from coordinated neuronal activity. Recent work exploring gamma oscillation entrainment raised the possibility that the phenomenon can be exploited to preserve neural function. In this issue of Neuron, Adaikkan et al. (2019) now show that chronic gamma entrainment using visual stimuli protects against several neurodegenerative phenotypes.
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