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Updated: Jan 23, 2026

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst
Published on: March 31, 2023
Intraoral epidermoid cyst with extensive elastofibromatous changes: an unusual finding
Heitor Albergoni Silveira1, Luciana Yamamoto Almeida2, Matheus Henrique Lopes Dominguete3
1Oral Medicine, Department of Diagnosis and Surgery, Araraquara Dental School, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.
Introduction:
Epidermoid cysts (ECs) are rare and occur in the head and neck regions with an incidence from 1.6 to 7% of all cysts. In the oral cavity, approximately 80 ECs have been reported, representing less than 0.01% of all cysts.
Case Report:
We report a case of a 26-year-old man who developed a large EC in the midline floor of the mouth causing nodular swelling in the submental region and speech and swallowing difficulties. The lesion was surgically excised by intraoral approach and microscopically revealed an EC associated with extensive elastofibromatous changes in the cystic capsule.
Conclusion:
Oral EC with extensive elastofibromatous changes is a finding extremely rare. The meaning of this finding is unknown, but a traumatic origin or deposit disorder of elastic fibers is suggested. To the best of our knowledge, intraoral EC with elastofibromatous changes has not been reported to date.
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