Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Phase Diagrams02:39

Phase Diagrams

49.5K
A phase diagram combines plots of pressure versus temperature for the liquid-gas, solid-liquid, and solid-gas phase-transition equilibria of a substance. These diagrams indicate the physical states that exist under specific conditions of pressure and temperature and also provide the pressure dependence of the phase-transition temperatures (melting points, sublimation points, boiling points). Regions or areas labeled solid, liquid, and gas represent single phases, while lines or curves represent...
49.5K
Uncertainty in Measurement: Reading Instruments02:46

Uncertainty in Measurement: Reading Instruments

50.9K
Counting is the type of measurement that is free from uncertainty, provided the number of objects being counted does not change during the process. Such measurements result in exact numbers. By counting the eggs in a carton, for instance, one can determine exactly how many eggs are there in the carton. Similarly, the numbers of defined quantities are also exact. For example, 1 foot is exactly 12 inches, 1 inch is exactly 2.54 centimeters, and 1 gram is exactly 0.001 kilograms. Quantities...
50.9K
Molecular and Ionic Solids02:54

Molecular and Ionic Solids

20.0K
Crystalline solids are divided into four types: molecular, ionic, metallic, and covalent network based on the type of constituent units and their interparticle interactions.
Molecular Solids
Molecular crystalline solids, such as ice, sucrose (table sugar), and iodine, are solids that are composed of neutral molecules as their constituent units. These molecules are held together by weak intermolecular forces such as London dispersion forces, dipole-dipole interactions, or hydrogen bonds, which...
20.0K
Metallic Solids02:37

Metallic Solids

20.5K
Metallic solids such as crystals of copper, aluminum, and iron are formed by metal atoms. The structure of metallic crystals is often described as a uniform distribution of atomic nuclei within a “sea” of delocalized electrons. The atoms within such a metallic solid are held together by a unique force known as metallic bonding that gives rise to many useful and varied bulk properties.
All metallic solids exhibit high thermal and electrical conductivity, metallic luster, and malleability....
20.5K
Structures of Solids02:22

Structures of Solids

17.5K
Solids in which the atoms, ions, or molecules are arranged in a definite repeating pattern are known as crystalline solids. Metals and ionic compounds typically form ordered, crystalline solids. A crystalline solid has a precise melting temperature because each atom or molecule of the same type is held in place with the same forces or energy. Amorphous solids or non-crystalline solids (or, sometimes, glasses) which lack an ordered internal structure and are randomly arranged. Substances that...
17.5K
Phase Transitions02:31

Phase Transitions

22.8K
Whether solid, liquid, or gas, a substance's state depends on the order and arrangement of its particles (atoms, molecules, or ions). Particles in the solid pack closely together, generally in a pattern. The particles vibrate about their fixed positions but do not move or squeeze past their neighbors. In liquids, although the particles are closely spaced, they are randomly arranged. The position of the particles are not fixed—that is, they are free to move past their neighbors to...
22.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Toward a Comparable Reactivity Framework for Type I Photoinitiators in Photocleavage, Photopolymerization and Light-Driven Additive Manufacturing.

Journal of the American Chemical Society·2026
Same author

Ageing of inverse vulcanised polymers.

RSC applied polymers·2026
Same author

Uncovering Aggregation-Induced Emission in Carbon Dots for Color-Changing Hydrogels and Information Encryption.

Angewandte Chemie (International ed. in English)·2026
Same author

Macromolecules with Tunable Fluorescence via Photochemical Step-Growth Polymerization.

ACS macro letters·2026
Same author

Understanding Wavelength-Dependent Photopolymerizations via Nano-Second Resolved Transient Spectroscopy.

Journal of the American Chemical Society·2026
Same author

Following the formation of single-chain nanoparticles generated by interblock crosslinking within diblock copolymers: a Monte Carlo simulation study with adjustable interaction strength between the blocks.

Soft matter·2026

Related Experiment Video

Updated: Jan 23, 2026

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
05:15

Solid-phase Synthesis of [4.4] Spirocyclic Oximes

Published on: February 6, 2019

7.3K

A Photochemical Ligation System Enabling Solid-Phase Chemiluminescence Read-Out.

Laura Delafresnaye1, Christian W Schmitt1, Leonie Barner1

  • 1School of Chemistry, Physics and Mechanical Engineering, Institute for Future Environments, Queensland University of, Technology (QUT), 2 George St, Brisbane, QLD 4000, Australia.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|June 8, 2019
PubMed
Summary

Researchers developed a novel "2-in-1" fluorescent probe for detecting hydrogen peroxide (H2O2) using photochemistry. This new probe simplifies detection and can be integrated into materials for advanced applications.

Keywords:
chemiluminescencefluorescencemicrosphereperoxyoxalatetetrazole

More Related Videos

An Inexpensive Adaptation of a Commercial Microwave Reactor for Solid Phase Peptide Synthesis
06:19

An Inexpensive Adaptation of a Commercial Microwave Reactor for Solid Phase Peptide Synthesis

Published on: November 22, 2024

798
A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting
08:57

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting

Published on: March 9, 2017

8.9K

Related Experiment Videos

Last Updated: Jan 23, 2026

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
05:15

Solid-phase Synthesis of [4.4] Spirocyclic Oximes

Published on: February 6, 2019

7.3K
An Inexpensive Adaptation of a Commercial Microwave Reactor for Solid Phase Peptide Synthesis
06:19

An Inexpensive Adaptation of a Commercial Microwave Reactor for Solid Phase Peptide Synthesis

Published on: November 22, 2024

798
A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting
08:57

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting

Published on: March 9, 2017

8.9K

Area of Science:

  • Chemical synthesis
  • Analytical chemistry
  • Materials science

Background:

  • Peroxyoxalate chemiluminescence (PO-CL) is a powerful hydrogen peroxide (H2O2) detection method.
  • The traditional two-component PO-CL system (peroxyoxalate and fluorophore) has limitations.
  • Existing methods require specific conditions, limiting broad applicability.

Purpose of the Study:

  • To develop an innovative photochemical platform for synthesizing "2-in-1" fluorescent probes.
  • To create inherently fluorescent peroxyoxalate probes using the nitrile imine-mediated tetrazole-ene cycloaddition (NITEC) reaction.
  • To demonstrate the utility of these probes in H2O2 detection and material integration.

Main Methods:

  • Synthesis of novel "2-in-1" peroxyoxalate-tetrazole (PO-Tz) probes via NITEC reaction.
  • Investigation of chemiluminescence properties (color emission) based on tetrazole structure.
  • Detection of hydrogen peroxide (H2O2) in nanomolar concentrations.
  • Grafting of PO-Tz probes onto poly(divinylbenzene) (PDVB) particles for solid-phase applications.

Main Results:

  • Successfully synthesized inherently fluorescent "2-in-1" PO-Tz probes.
  • Demonstrated H2O2 detection with yellow or blue light emission, tunable by tetrazole structure.
  • Achieved sensitive H2O2 detection in the nanomolar range, even without base.
  • Successfully incorporated PO-Tz probes into polymeric materials (PDVB microspheres) for solid-phase chemiluminescence.

Conclusions:

  • The NITEC reaction provides a versatile photochemical platform for creating novel "2-in-1" fluorescent probes.
  • These probes offer a simplified and efficient method for H2O2 detection with tunable emission.
  • The ability to integrate probes into materials opens new avenues for solid-phase sensing applications.