Related Experiment Video
Updated: Jan 23, 2026

06:55
Protocol to Create Chronic Wounds in Diabetic Mice
Published on: September 25, 2019
21.6K
Depression risk among patients with chronic wounds
P Fino1, G Di Taranto, A Pierro
1Department of Surgery "P. Valdoni", UOC of Plastic Surgery, "Sapienza" University of Rome, Policlinico Umberto I, Rome, Italy. pasquale.fino@gmail.com.
Summary
Patients with chronic wounds show higher depression scores than healthy individuals. Addressing depression with a multidisciplinary approach may improve chronic wound healing and patient outcomes.
Area of Science:
- Medical Research
- Psychiatry
- Dermatology
Background:
- Chronic wounds, defined as those exceeding 6 weeks to heal, are linked to depression.
- Leg ulcers are frequently associated with depression among chronic skin conditions.
- Previous studies highlight the connection between chronic wounds and mental health.
Purpose of the Study:
- To determine the prevalence of depression in patients suffering from various types of chronic wounds.
- To compare depression levels in chronic wound patients versus healthy controls.
Main Methods:
- A cohort of 33 patients with chronic wounds and 33 matched healthy controls participated.
- The Beck Depression Inventory II (BDI-II) survey was administered to all participants.
- Patient demographics: mean age 71 years (range 25-87); control demographics: mean age 73 years (range 31-88).
Main Results:
- The average BDI-II score for patients with chronic wounds was 14.5.
- The average BDI-II score for healthy controls was 8.
- Patients with chronic wounds exhibited significantly higher depression scores.
Conclusions:
- Depression in chronic wound patients stems from multiple factors, necessitating a multidisciplinary treatment strategy.
- Improving patients' psycho-emotional state can enhance treatment compliance.
- Better compliance may lead to improved efficacy in managing chronic wounds.
Related Concept Videos
Long-term Depression
33.2K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.2K
Long-term Depression
3.1K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
Calcium Ion Concentration Mechanism
If over...
3.1K
Freezing Point Depression and Boiling Point Elevation
39.7K
Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
39.7K
Depressants
385
Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
385
Depression: Overview
815
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
815
Relative Risk
2.0K
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.0K

