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Alcohol use disorder relapse factors: A systematic review
Wilco Sliedrecht1, Ranne de Waart2, Katie Witkiewitz3
1De Hoop GGZ, Provincialeweg 70, 3329 KP Dordrecht, the Netherlands.
Understanding Alcohol Use Disorder (AUD) relapse is crucial. Key relapse triggers include psychiatric issues and substance use, while social support and self-efficacy can prevent relapse in AUD patients.
Area of Science:
- Addiction Medicine
- Psychiatry
- Public Health
Background:
- Relapsing-remitting course is common in Alcohol Use Disorder (AUD).
- Identifying factors associated with alcohol resumption is challenging.
- Understanding relapse determinants is vital for effective AUD treatment.
Purpose of the Study:
- To systematically review recent literature (2000-2019) on determinants of Alcohol Use Disorder relapse.
- To identify specific factors significantly associated with and protective against AUD relapse.
Main Methods:
- Systematic review of 4613 identified papers, with 321 articles included.
- Consulted relevant databases for articles reporting statistically significant relapse determinants.
- Employed a descriptive methodology, categorizing determinants into biopsychosocial and spiritual domains.
Main Results:
- Psychiatric co-morbidity, AUD severity, craving, co-use of other substances, and health/social factors significantly predict AUD relapse.
- Supportive social networks, self-efficacy, and finding purpose/meaning in life are protective factors against relapse.
- Findings highlight a complex interplay of factors influencing AUD relapse and recovery.
Conclusions:
- Consistent identification of significant risk and protective factors for AUD relapse.
- Findings can inform personalized medicine approaches for improved AUD patient outcomes.
- Further research can refine understanding of relapse dynamics in Alcohol Use Disorder.
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