Effect of a Combined Stretching and Strength Training Program on Gait Function in Children with Cerebral Palsy, GMFCS

Merete Aarsland Fosdahl1,2, Reidun Jahnsen3,4, Kristin Kvalheim5

  • 1Department of Clinical Neuroscience for Children, Division of Pediatric and Adolescent Medicine,Oslo University Hospital, 0424 Oslo, Norway. mfosdahl@ous-hf.no.

Insights

A combined stretching and progressive resistance exercise program did not improve gait function in children with cerebral palsy (CP). The intervention did not show significant differences compared to usual care for most gait parameters.

Area of Science:

  • Pediatrics
  • Neurology
  • Rehabilitation Medicine

Background:

  • Ambulant children with cerebral palsy (CP) frequently exhibit impaired gait.
  • Reduced active knee extension is a common contributing factor to gait dysfunction in CP.
  • Targeting active knee extension is a potential therapeutic strategy for improving gait in CP.

Purpose of the Study:

  • To evaluate the efficacy of a combined intervention program of stretching and progressive resistance exercise (PRE) on gait function in children with spastic CP.
  • To assess the impact of the intervention on specific gait parameters including kinematics, step length, speed, Gait Deviation Index (GDI), and Six-Minute Walk test (6MWT).

Main Methods:

  • A randomized controlled trial involving 37 ambulant children with CP (Gross Motor Function Classification System I-III).
  • Intervention group received a 16-week combined stretching and PRE program followed by a 16-week maintenance program.
  • Comparison group received usual care.
  • Gait analysis utilized three-dimensional gait analysis (3DGA) and the 6MWT at baseline, 16, and 32 weeks.

Main Results:

  • No statistically significant differences in gait parameters were observed between the intervention and comparison groups at 16 and 32 weeks.
  • Both groups showed significant improvements in gait distance on the 6MWT, with no inter-group differences.
  • The combined intervention did not yield superior gait improvements compared to usual care.

Conclusions:

  • A 16-week combined stretching and PRE program, followed by a maintenance phase, did not significantly improve gait function in ambulant children with CP.
  • The findings suggest that this specific exercise regimen may not be sufficient to alter gait parameters in this population.
  • Further research is needed to explore alternative or modified interventions for improving gait in children with CP.

Related Concept Videos

The Equilibrium Binding Constant and Binding Strength02:18

The Equilibrium Binding Constant and Binding Strength

The equilibrium binding constant (Kb) quantifies the strength of a protein-ligand interaction. Kb can be calculated as follows when the reaction is at equilibrium:
14.9K
Transfer Function in Control Systems01:21

Transfer Function in Control Systems

The transfer function is a fundamental concept in the analysis and design of linear time-invariant (LTI) systems. It offers a concise way to understand how a system responds to different inputs in the frequency domain. It serves as a bridge between the time-domain differential equations that describe system dynamics and the frequency-domain representation that facilitates easier manipulation and analysis.
To derive the transfer function, consider a general nth-order linear time-invariant...
1.5K
Acid Strength and Molecular Structure03:05

Acid Strength and Molecular Structure

Binary Acids and Bases
In the absence of any leveling effect, the acid strength of binary compounds of hydrogen with nonmetals (A) increases as the H-A bond strength decreases down a group in the periodic table. For group 17, the order of increasing acidity is HF < HCl < HBr < HI. Likewise, for group 16, the order of increasing acid strength is H2O < H2S < H2Se < H2Te. Across a row in the periodic table, the acid strength of binary hydrogen compounds increases with increasing...
32.9K
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.2K
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
4.7K
Trial and Error and Algorithm01:12

Trial and Error and Algorithm

A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
403