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Updated: Jan 23, 2026

Characterization of the Sense of Agency over the Actions of Neural-machine Interface-operated Prostheses
Published on: January 7, 2019
Photochemistry of Organic Retinal Prostheses
Giovanni Manfredi1, Elisabetta Colombo2, Jonathan Barsotti1
1Center for Nano Science and Technology, Istituto Italiano di Tecnologia, 20133 Milan, Italy; email: giovanni.manfredi@iit.it , guglielmo.lanzani@iit.it.
Abstract:
Organic devices are attracting considerable attention as prostheses for the recovery of retinal light sensitivity lost to retinal degenerative disease. The biotic/abiotic interface created when light-sensitive polymers and living tissues are placed in contact allows excitation of a response in blind laboratory rats exposed to visual stimuli. Although polymer retinal prostheses have proved to be efficient, their working mechanism is far from being fully understood. In this review article, we discuss the results of the studies conducted on these kinds of polymer devices and compare them with the data found in the literature for inorganic retinal prostheses, where the working mechanisms are better comprehended. This comparison, which tries to set some reference values and figures of merit, is intended for use as a starting point to determine the direction for further investigation.
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