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Updated: Jan 23, 2026

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
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Myoclonic status epilepticus induced by cefepime overdose requiring haemodialysis

Aude Garin1, Florent Bavozet1

  • 1Department of Intensive Care, Centre Hospitalier Victor Jousselin, Dreux, France.

BMJ Case Reports
|June 9, 2019
PubMed

Insights

We describe a case of cefepime neurotoxicity, a serious adverse effect of this antibiotic, presenting as seizures and coma in a patient with kidney failure. Hemodialysis was used to manage this condition.

Area of Science:

  • Pharmacology
  • Neurology
  • Nephrology

Background:

  • Cefepime is a fourth-generation cephalosporin antibiotic.
  • It is used for hospital-acquired Gram-negative infections.
  • Neurotoxicity is a known adverse effect, especially in renal impairment.
Keywords:
dialysisepilepsy and seizureshealthcare improvement and patient safetyunwanted effects/adverse reactions

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