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Updated: Jan 23, 2026

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry
Published on: January 12, 2018
Comprehensive Analysis of Red Blood Cell Distribution Width as a Preoperative Prognostic Predictor in Gastric Cancer
Noriyuki Hirahara1, Yoshitsugu Tajima2, Yusuke Fujii2
1Department of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan norinorihirahara@yahoo.co.jp.
Background/Aim:
The aim of the current study was to investigate the impact of the preoperative red cell distribution width (RDW) value on the overall survival (OS) and cancer-specific survival (CSS) of gastric cancer patients.
Patients And Methods:
A total of 366 gastric cancer patients who underwent curative gastrectomy were retrospectively reviewed. Among them, RDW was evaluated in 165 non-elderly and 201 elderly patients.
Results:
Multivariate analysis revealed that pathological stage (pStage), RDW, and carcinoembryonic antigen (CEA), were independent prognostic factors of OS, while pStage and RDW were independent prognostic factors of CSS. In non-elderly patients, based on the multivariate analysis, pStage, adjuvant chemotherapy, and RDW were identified as independent prognostic factors of OS. In elderly patients, RDW was identified as independent prognostic factors of OS and CSS.
Conclusion:
Preoperative RDW is a promising independent prognostic factor in gastric cancer.
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