Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Observational Studies01:11

Observational Studies

10.8K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
10.8K
Pilot and Numeric Relaying01:21

Pilot and Numeric Relaying

485
Pilot relaying is a type of differential protection used in power systems. It compares electrical quantities at the terminals of equipment via a communication channel instead of direct relay interconnection. This method is essential for transmission lines where the terminals are far apart, typically up to 80 km for lines with 69 to 115 kV ratings. Four types of communication channels are used for pilot relaying:
485
Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

807
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
807
Serum Studies: Renal Function Tests01:24

Serum Studies: Renal Function Tests

385
Renal function tests are crucial for assessing kidney health, monitoring disease progression, and evaluating the kidneys' efficiency in waste elimination, fluid balance, and electrolyte regulation. These tests offer critical insights into kidney function, even though routine measurements may appear normal until there is a significant decline in the glomerular filtration rate or GFR. Typically, signs of kidney impairment only become evident when the GFR falls to about 50% of its normal level.
385
Kendall's Tau Test01:16

Kendall's Tau Test

1.1K
Kendall's tau test, also known as the Kendall rank coefficient test, is a nonparametric method for assessing association between two variables. This test is particularly useful for identifying significant correlations when the distributions of the sample and population are unknown. Developed in 1938 by the British statistician Sir Maurice George Kendall, the tau coefficient (denoted as τ) serves as a rank correlation coefficient, with values ranging from -1 to +1.
A τ value of +1 indicates...
1.1K
Drug Dosing in Renal Diseases: Measurement of Serum Creatinine Concentration and Clearance01:25

Drug Dosing in Renal Diseases: Measurement of Serum Creatinine Concentration and Clearance

191
In healthy individuals, serum creatinine levels remain stable due to a balance between its constant production—primarily from muscle metabolism—and renal excretion. Creatinine is freely filtered by the glomeruli, making it a valuable marker for estimating renal function. When the glomerular filtration rate (GFR) decreases, the kidneys can only eliminate less creatinine, causing serum levels to rise.Serum creatinine concentration is widely used to estimate creatinine clearance...
191

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Use of Hyperbaric Oxygen in Patients with Necrotizing Soft Tissue Infections: A Scandinavian Multicenter, Prospective, Observational Cohort.

Infectious diseases and therapy·2025
Same author

Radiation-induced cystitis treated with hyperbaric oxygen therapy (RICH-ART): long-term follow-up of a randomised controlled, phase 2-3 trial.

EClinicalMedicine·2025
Same author

Prevalence of EBV, HHV6, HCMV, HAdV, SARS-CoV-2, and Autoantibodies to Type I Interferon in Sputum from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients.

Viruses·2025
Same author

An experimental comparison and user evaluation of three different dried plasma products.

Vox sanguinis·2025
Same author

Coagulation and platelet function in cold-stored whole blood on missions in a helicopter emergency service.

Acta anaesthesiologica Scandinavica·2025
Same author

Civilian pattern of injuries in armed conflicts - a systematic review.

Scandinavian journal of trauma, resuscitation and emergency medicine·2024

Related Experiment Video

Updated: Jan 23, 2026

Training Rats to Voluntarily Dive Underwater: Investigations of the Mammalian Diving Response
11:56

Training Rats to Voluntarily Dive Underwater: Investigations of the Mammalian Diving Response

Published on: November 12, 2014

12.8K

Serum tau concentration after diving - an observational pilot study.

Anders Rosén1,2, Nicklas Oscarsson3, Andreas Kvarnström1

  • 1Department of Anesthesia and Intensive Care Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.

Diving and Hyperbaric Medicine
|June 10, 2019
PubMed
Summary

Repeated deep dives significantly increase serum tau protein levels, a potential indicator of neuronal stress. This study found no correlation between tau protein and venous gas emboli after diving.

Keywords:
BiomarkersCentral nervous systemDecompression sicknessDiving researchStressTau proteinVenous gas emboli

More Related Videos

A Pilot Study on the Repetitive Transcranial Magnetic Stimulation of Aβ and Tau Levels in Rhesus Monkey Cerebrospinal Fluid
06:22

A Pilot Study on the Repetitive Transcranial Magnetic Stimulation of Aβ and Tau Levels in Rhesus Monkey Cerebrospinal Fluid

Published on: September 3, 2021

4.0K
Operation of a 25 KWth Calcium Looping Pilot-plant with High Oxygen Concentrations in the Calciner
06:34

Operation of a 25 KWth Calcium Looping Pilot-plant with High Oxygen Concentrations in the Calciner

Published on: October 25, 2017

8.3K

Related Experiment Videos

Last Updated: Jan 23, 2026

Training Rats to Voluntarily Dive Underwater: Investigations of the Mammalian Diving Response
11:56

Training Rats to Voluntarily Dive Underwater: Investigations of the Mammalian Diving Response

Published on: November 12, 2014

12.8K
A Pilot Study on the Repetitive Transcranial Magnetic Stimulation of Aβ and Tau Levels in Rhesus Monkey Cerebrospinal Fluid
06:22

A Pilot Study on the Repetitive Transcranial Magnetic Stimulation of Aβ and Tau Levels in Rhesus Monkey Cerebrospinal Fluid

Published on: September 3, 2021

4.0K
Operation of a 25 KWth Calcium Looping Pilot-plant with High Oxygen Concentrations in the Calciner
06:34

Operation of a 25 KWth Calcium Looping Pilot-plant with High Oxygen Concentrations in the Calciner

Published on: October 25, 2017

8.3K

Area of Science:

  • Neurology
  • Sports Medicine
  • Physiology

Background:

  • Elevated tau protein concentrations are linked to central nervous system conditions like Alzheimer's disease, TBI, and hypoxia.
  • The impact of diving on serum tau protein levels remains largely unknown.
  • This study investigates potential neurological effects of diving.

Purpose of the Study:

  • To examine changes in serum tau protein concentrations following diving.
  • To determine the relationship between diving and increased tau protein.
  • To assess if venous gas emboli (VGE) correlate with tau protein levels.

Main Methods:

  • A prospective observational pilot study involving 10 navy divers.
  • Divers performed 1-2 dives daily at depths of 52-90 msw over four days using air or trimix.
  • Serum samples were collected pre- and post-dive; venous gas emboli (VGE) were monitored using Doppler ultrasound.

Main Results:

  • Serum tau protein concentrations significantly increased post-diving (P = 0.016).
  • Median tau protein rose from 0.200 pg·mL⁻¹ to 0.450 pg·mL⁻¹.
  • No significant changes were observed in glial fibrillary acidic protein or neurofilament light protein; no correlation found between tau protein and VGE.

Conclusions:

  • Repeated diving to depths of 52-90 msw is associated with a statistically significant increase in serum tau protein.
  • This elevation in tau protein may suggest neuronal stress induced by deep diving.
  • Further research is needed to understand the long-term implications of these findings.