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Updated: Jan 23, 2026

Engineering Biological-Based Vascular Grafts Using a Pulsatile Bioreactor
Published on: June 14, 2011
Schneider K Rancy1, Gernot Schmidle2, Scott W Wolfe3
1College of Medicine, SUNY Downstate Medical Center, 1160 Ocean Avenue, Apt 5F, Brooklyn, NY 11230, USA.
Abstract:
Many hand surgeons argue that vascularized bone grafting is indicated in proximal pole avascular necrosis, prior failed surgery, or long-standing scaphoid nonunion. However, the available evidence does not support improved treatment outcomes for vascularized bone grafting rather than traditional nonvascularized techniques. This article addresses the available evidence and examines the role of vascularized bone grafting in scaphoid nonunion treatment. It also identifies important factors that influence healing, clarifies the decision-making algorithm, and proposes areas for further research.
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