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The Gardner syndrome.

K Antoniades1, I Eleftheriades, D Karakasis

  • 1Department of Oral and Maxillofacial Surgery, Aristotle's University of Thessaloniki, Greece.

International Journal of Oral and Maxillofacial Surgery
|August 1, 1987
PubMed
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Gardner syndrome, a genetic disorder, involves colon polyps and tumors. This case highlights a 17-year-old male with characteristic Gardner syndrome lesions, including jaw tumors and a mandibular odontoma.

Area of Science:

  • Medical Genetics
  • Oncology
  • Oral and Maxillofacial Surgery

Background:

  • Gardner syndrome is an autosomal dominant condition, a variant of familial adenomatous polyposis.
  • It is characterized by colonic polyposis, numerous benign tumors of the skin and soft tissues, and osteomas of the jaw.

Observation:

  • A 17-year-old male presented with bilateral, painless, hard swellings on the mandible.
  • The patient exhibited the classic triad of Gardner syndrome lesions.
  • Panoramic radiography revealed characteristic radio-opaque jaw lesions (exostoses and enostoses).

Findings:

  • A compound odontoma was identified on the left side of the mandible.
  • The radiographic findings correlated with the clinical presentation of Gardner syndrome.

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  • The case underscores the importance of recognizing the oral manifestations of Gardner syndrome.

    • Implications:

    • Early diagnosis of Gardner syndrome is crucial for timely management of associated risks, particularly colorectal cancer.
    • Dental and maxillofacial evaluations are vital for identifying potential osteomas and odontomas in suspected cases.
    • This case contributes to the understanding of the diverse clinical spectrum of Gardner syndrome.