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Linkage analysis of neurofibromatosis
1Department of Pediatrics, Johns Hopkins Institution, Baltimore, Maryland.
Journal of Medical Genetics
|September 1, 1987
Abstract:
Linkage analysis of neurofibromatosis was performed using genes on chromosomes 1, 8, 11, and 12. No linkage was found between NF and C-myc, AT 3, IGF-1, PTH, and gamma globin genes. Evidence for linkage was found between C-ets 1, on the long arm of chromosome 11 and NF in two families with a lod score of 1.88 at theta = 0. More families are being studied to confirm this linkage.