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In thoracic aortic surgery, is innominate artery cannulation a safe and effective alternative to axillary artery
Amer Harky1, Ciaran Grafton-Clarke2, Max Hadlett3
1Department of Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, Liverpool, UK.
Insights
Innominate artery cannulation is a safe and effective alternative to axillary artery cannulation for thoracic aortic surgery. Both methods show similar mortality rates and neuroprotection, with innominate artery cannulation potentially offering a slight stroke reduction.
Area of Science:
- Cardiovascular Surgery
- Thoracic Aortic Surgery
- Surgical Cannulation Techniques
Background:
- Thoracic aortic surgery necessitates effective cannulation strategies for patient outcomes.
- Axillary artery cannulation is a common approach, but alternatives are explored for improved safety and efficacy.
Purpose of the Study:
- To compare the postoperative outcomes of innominate artery cannulation versus axillary artery cannulation in patients undergoing thoracic aortic surgery.
- To determine if innominate artery cannulation offers superior or non-inferior results compared to axillary artery cannulation.
Main Methods:
- A systematic review and best-evidence topic synthesis was conducted.
- Five studies, including a randomized trial and observational cohorts, comprising 1338 patients (616 innominate, 722 axillary) were analyzed.
Main Results:
- No statistically significant difference in 30-day or in-hospital mortality was observed between innominate and axillary artery cannulation (P > 0.05).
- Stroke incidence was slightly lower with innominate artery cannulation in three of four studies, though not statistically significant (P > 0.05).
Conclusions:
- Innominate artery cannulation is non-inferior to axillary artery cannulation for thoracic aortic surgery.
- Both techniques offer comparable neuroprotection and are not associated with increased mortality, making innominate artery cannulation a viable alternative.
Abstract:
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was: in a patient undergoing thoracic aortic surgery, is innominate artery cannulation superior to axillary artery cannulation in terms of postoperative outcomes? Five hundred and thirty-one papers were found using the reported search strategy, of which 5 represented the best evidence to answer the clinical question. A total of 1338 participants were included across the 5 studies. Seven hundred and twenty-two patients were cannulated via the axillary artery and 616 were cannulated via the innominate artery. The included 5 studies were 2 prospective observational cohorts, 2 retrospective case-series analysis and a single-blinded randomized trial. Thirty-day or in-hospital mortality rates were reported in all 5 studies. There were no significant differences in mortality with innominate artery cannulation compared to axillary artery cannulation (P > 0.05), with slightly lower mortality rates in 2 studies, slightly higher mortality rates in 2 and equal in 1 study. Though statistical significance was not demonstrated (P > 0.05), a stroke occurred slightly less frequently in patients receiving innominate artery cannulation compared to axillary artery cannulation in 3 of the 4 studies. Innominate artery cannulation is non-inferior to axillary artery cannulation for thoracic aortic surgery, with a similar level of neuroprotection and is not associated with increased levels of mortality.
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