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A Predictive Model for Identification of Children at Risk of Subsequent High-Frequency Utilization of the Emergency
Margaret E Samuels-Kalow1, Matthew W Bryan2, Marilyn Sawyer Sommers3
1From the Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Insights
Predicting high emergency department (ED) use for childhood asthma is possible using administrative data. Models incorporating clinical data did not improve prediction accuracy for subsequent ED visits.
Area of Science:
- Pediatric Emergency Medicine
- Health Services Research
- Clinical Informatics
Background:
- Childhood asthma is a leading cause of frequent emergency department (ED) visits.
- Predicting future ED utilization in pediatric asthma patients is crucial for resource allocation and intervention.
- Existing methods for predicting subsequent ED visits among pediatric asthma patients in the ED are not well-defined.
Purpose of the Study:
- To develop and validate a predictive model identifying children in the ED at high risk for subsequent frequent asthma-related ED utilization.
- To evaluate the impact of including clinical data on the predictive performance of the model.
Main Methods:
- Utilized 3 years (2013-2015) of electronic health records from a tertiary urban children's hospital.
- Developed and tested three multivariable predictive models using derivation and validation sets (50% each).
- Evaluated model performance using error rates, receiver operating characteristic (ROC) curves, and optimal cutpoints.
Main Results:
- 125 out of 5535 patients (2.3%) experienced 4 or more asthma-related ED visits in the outcome year.
- Key predictors included age and prior ED visits for asthma; clinical data did not enhance prediction.
- Models achieved areas under the ROC curve ranging from 0.77 to 0.80.
Conclusions:
- Administrative data available during ED triage effectively predict subsequent high ED utilization for pediatric asthma.
- The addition of clinical variables did not significantly improve the predictive power of the models.
- These validated models can serve as valuable tools for research on intervention efficacy in high-risk pediatric asthma populations.
Background:
Asthma is the most common chronic condition among children with high-frequency emergency department (ED) utilization. Previous research has shown in outpatients seen for asthma that acute care visits predict subsequent health care utilization. Among ED patients, however, the optimal method of predicting subsequent ED utilization remains to be described. The goal of this study was to create a predictive model to identify children in the ED who are at risk of subsequent high-frequency utilization of the ED for asthma.
Methods:
We used 3 years of data, 2013-2015, drawn from the electronic health records at a tertiary care, urban, children's hospital that is a high-volume center for asthma care. Data were split into a derivation (50%) and validation/test (50%) set, and 3 models were created for testing: (1) all index patients; (2) removing patients with complex chronic conditions; and (3) subset of patients with in-network care on whom more clinical data were available. Each multivariable model was then tested in the validation set, and its performance evaluated by predicting error rate, calculation of a receiver operating characteristic (ROC) curve, and identification of the optimal cutpoint to maximize sensitivity and specificity.
Results:
There were 5535 patients with index ED visits, of whom 2767 were in the derivation set and 2768 in the validation set. Of the 5535 patients, 125 patients (2.3%) had 4 or more visits for asthma in the outcome year. Significant predictors in models 1 and 2 were age and number of prior ED visits for asthma. For model 3 (additional clinical information available), the predictors were number of prior ED visits for asthma, number of primary care visits, and not having a controller medication. Areas under the ROC curve were 0.77 for model 1, 0.80 for model 2, and 0.77 for model 3.
Conclusions:
Administrative data available at the time of ED triage can predict subsequent high utilization of the ED, with areas under the ROC curve of 0.77 to 0.80. The addition of clinical variables did not improve the model performance. These models provide useful tools for researchers interested in examining intervention efficacy by predicted risk group.
Related Concept Videos
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Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma: Pathogenesis and Management
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Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

