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Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves. While the first six innervate the head and neck, the latter six nerves innervate the head and neck, as well as organs and tissues in the thoracic and abdominal cavities. They facilitate communication, expression, and autonomic control within the human body.
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Related Experiment Video

Updated: Jan 23, 2026

Axoplasm Isolation from Rat Sciatic Nerve
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Sciatic Nerve Intraneural Hematoma.

Hussam Abou-Al-Shaar1, Mark A Mahan2

  • 1Department of Neurosurgery, Hofstra Northwell School of Medicine, Manhasset, New York, USA.

World Neurosurgery
|June 11, 2019
PubMed
Summary
This summary is machine-generated.

Intraneural hematomas, though rare, can cause nerve damage. This case highlights chronic hemorrhage within the sciatic nerve as a cause of severe sciatic palsy.

Keywords:
HemorrhageIntraneural hematomaSciatic nerve

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Area of Science:

  • Neurology
  • Pathology

Background:

  • Intraneural hematomas are an uncommon etiology of focal mononeuropathy.
  • They are typically associated with inherited/iatrogenic coagulopathies or nerve-targeting injections.

Observation:

  • A 68-year-old male on warfarin presented with a 6-month history of progressive sciatic nerve dysfunction.
  • Symptoms included weakness, severe pain, and numbness in the posterior left thigh and below the knee.
  • Imaging revealed a cystic mass on the sciatic nerve, initially misdiagnosed as a pseudotumor.

Findings:

  • Surgical exploration identified a hemorrhagic pseudocompartment within the sciatic nerve.
  • Histopathology confirmed chronic hemorrhage as the cause of the lesion.

Implications:

  • This case underscores the importance of considering intraneural hematomas in the differential diagnosis of nerve masses.
  • Recognition of these lesions is crucial for accurate diagnosis and management of peripheral nerve disorders.