Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

pre-mRNA Processing02:01

pre-mRNA Processing

57.2K
In eukaryotic cells, transcripts made by RNA polymerase are modified and processed before exiting the nucleus. Unprocessed RNA is called precursor mRNA or pre-mRNA to distinguish it from mature mRNA.
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a “cap” to the 5’ end of the growing transcript. In this process, a 5’ phosphate is replaced by modified guanosine that has a methyl group attached to it (7-Methyl...
57.2K
Pre-mRNA Processing: Modification of pre-mRNA Ends01:35

Pre-mRNA Processing: Modification of pre-mRNA Ends

14.2K
In eukaryotic cells, transcripts made by RNA polymerase are modified and processed before exiting the nucleus. Unprocessed RNA is called precursor mRNA or pre-mRNA to distinguish it from mature mRNA.
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a cap to the 5' end of the growing transcript. In this process, a 5' phosphate is replaced by modified guanosine that has a methyl group attached (7-methyl guanosine). This 5' cap helps...
14.2K
Chromatin Structure Regulates pre-mRNA Processing02:41

Chromatin Structure Regulates pre-mRNA Processing

8.1K
In eukaryotic cells, nascent mRNA transcripts need to undergo many post-transcriptional modifications to reach the cell cytoplasm and translate into functional proteins. For a long time, transcription and pre-mRNA processing were considered two independent events that occur sequentially in the cell. However, it has now been well established that transcription and pre-mRNA processing are two simultaneous processes that are precisely regulated inside the cell.
The chromatin structure, especially...
8.1K
Tracheostomy Care I: Pre-procedural Steps01:16

Tracheostomy Care I: Pre-procedural Steps

1.0K
A tracheostomy is a surgical technique that involves making an incision in the neck to provide access to the trachea. It is frequently used in medical conditions such as airway obstruction and prolonged mechanical ventilation. Effective nursing management is crucial for the long-term success of a tracheostomy.
Required Equipment
The equipment necessary for tracheostomy care includes:
1.0K
Pre-mRNA Processing: RNA Splicing01:36

Pre-mRNA Processing: RNA Splicing

6.7K
6.7K
Tracheostomy Suctioning I: Pre-Procedural Steps01:26

Tracheostomy Suctioning I: Pre-Procedural Steps

2.2K
Tracheostomy suctioning is a critical procedure healthcare professionals perform to maintain a patent airway in patients with a tracheostomy tube. This procedure is necessary when secretions accumulate in the airway, causing respiratory distress. Here is a step-wise procedural guide for performing tracheostomy suctioning using an open system.
Equipment Required
First, gather all necessary equipment: a sterile suction catheter, a sterile disposable container, sterile gloves, a towel or...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparing functionality, anxiety and depression during pregnancy and postpartum in women with hypertensive disorders: Findings from the WOICE assessment.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026
Same author

The hypothalamic-neurohypophyseal system in preeclampsia: a systematic review with a subgroup meta-analysis of copeptin levels worldwide.

Frontiers in endocrinology·2026
Same author

Prevalence and determinants of fully vaccinated status for COVID-19 among pregnant women in Brazil, Ghana, Kenya, and Pakistan.

Vaccine·2026
Same author

Validation of the fullPIERS model for predicting severe maternal outcomes in preeclampsia in five Brazilian centers.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026
Same author

Evaluation of the uptake and usability of the pregnant women surveillance system (SIMG): A cross-sectional pilot study.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026
Same author

Gamma SARS-CoV-2 variant of concern infection repercussions on pregnancy outcomes: A translational cohort study.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026

Related Experiment Video

Updated: Jan 23, 2026

FISH for Pre-implantation Genetic Diagnosis
07:34

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

37.8K

Pre-eclampsia/Eclampsia.

José Carlos Peraçoli1, Vera Therezinha Medeiros Borges1, José Geraldo Lopes Ramos2

  • 1Department of Gynecology and Obstetrics, Botucatu Medical School, Universidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, SP, Brazil.

Revista Brasileira De Ginecologia E Obstetricia : Revista Da Federacao Brasileira Das Sociedades De Ginecologia E Obstetricia
|June 11, 2019
PubMed
Summary

Pre-eclampsia, a pregnancy complication, involves high blood pressure and organ damage. This review covers its causes, diagnosis, management, and long-term effects for clinical care.

More Related Videos

A Pre-Clinical Porcine Model of Orthotopic Heart Transplantation
09:12

A Pre-Clinical Porcine Model of Orthotopic Heart Transplantation

Published on: April 27, 2019

10.1K
Pre-clinical Orthotopic Murine Model of Human Prostate Cancer
07:01

Pre-clinical Orthotopic Murine Model of Human Prostate Cancer

Published on: August 29, 2016

15.0K

Related Experiment Videos

Last Updated: Jan 23, 2026

FISH for Pre-implantation Genetic Diagnosis
07:34

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

37.8K
A Pre-Clinical Porcine Model of Orthotopic Heart Transplantation
09:12

A Pre-Clinical Porcine Model of Orthotopic Heart Transplantation

Published on: April 27, 2019

10.1K
Pre-clinical Orthotopic Murine Model of Human Prostate Cancer
07:01

Pre-clinical Orthotopic Murine Model of Human Prostate Cancer

Published on: August 29, 2016

15.0K

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Cardiovascular Disease in Pregnancy

Background:

  • Pre-eclampsia is a serious pregnancy-specific condition characterized by hypertension and potential organ damage.
  • Diagnosis typically involves hypertension and proteinuria after 20 weeks gestation, or organ damage without proteinuria.
  • Etiology remains largely unknown, necessitating a comprehensive review of current understanding.

Purpose of the Study:

  • To provide a general overview of pre-eclampsia for clinical and obstetric care.
  • To explore current knowledge on etiology, pathophysiology, diagnosis, prediction, outcomes, and prevention.
  • To detail management strategies for hypertensive crises, eclampsia, and obstetric care based on disease severity and gestational age.

Main Methods:

  • This is a review article, synthesizing existing literature and clinical knowledge.
  • Focuses on practical aspects relevant to healthcare providers.
  • Covers etiological theories, diagnostic criteria, predictive approaches, and management protocols.

Main Results:

  • Management strategies are presented for both severe and non-severe pre-eclampsia, including hypertensive emergencies.
  • Obstetric management is stratified by gestational age and clinical status, guiding delivery decisions.
  • The review addresses immediate postpartum care and long-term health implications for affected women.

Conclusions:

  • Effective clinical and obstetric management of pre-eclampsia requires a multifaceted approach.
  • Understanding prediction, prevention, and long-term sequelae is crucial for comprehensive maternal care.
  • This review offers a practical guide for healthcare professionals managing pre-eclampsia throughout gestation and postpartum.