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Arterial ischemic stroke in non-neonate children: Diagnostic and therapeutic specificities

M Kossorotoff1, S Chabrier2, K Tran Dong3

  • 1French Center for Pediatric Stroke, France; Pediatric neurology, AP-HP, university hospital Necker-Enfants-malades, INSERM U894, 75015 Paris, France.

Revue Neurologique
|June 12, 2019
PubMed

Insights

Pediatric arterial ischemic stroke (AIS) requires prompt recognition and specialized care. Early diagnosis and tailored treatments significantly improve outcomes for affected children.

Area of Science:

  • Neurology
  • Pediatrics
  • Vascular Medicine

Background:

  • Pediatric arterial ischemic stroke (AIS) causes severe, long-term motor and cognitive impairments.
  • It impacts academic achievement, social integration, and life prospects for children.

Purpose of the Study:

  • To outline key elements for improving pediatric AIS management and outcomes.
  • To highlight specific considerations for focal cerebral arteriopathy, sickle cell disease, and moyamoya.

Main Methods:

  • Emphasizes early symptom awareness and pediatric stroke code protocols.
  • Recommends MRI-first imaging and tailored acute phase management.
  • Stresses individualized recanalization strategies and multidisciplinary rehabilitation.

Main Results:

  • Awareness, rapid protocols, and tailored treatments are crucial for better pediatric AIS outcomes.
  • Focal cerebral arteriopathy is a primary cause, necessitating specific management.
  • Adapted screening and therapeutics are vital for sickle cell disease and moyamoya patients.

Conclusions:

  • Optimizing pediatric AIS management involves a multi-faceted approach from acute care to long-term rehabilitation.
  • Specific etiologies like focal cerebral arteriopathy and sickle cell disease require distinct therapeutic pathways.

Keywords:
ChildrenFocal cerebral arteriopathyRehabilitationStrokeStroke codeThrombolysis

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