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6,6'-Dihydroxythiobinupharidine as a poison of human type II topoisomerases

Esha D Dalvie1, Jacob Gopas2, Avi Golan-Goldhirsh3

  • 1Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232-0146, USA.

Bioorganic & Medicinal Chemistry Letters
|June 12, 2019
PubMed

Keywords:
6,6’-DihydroxythiobinupharidineCovalent poisonDNA cleavageTopoisomerase IIαTopoisomerase IIβ

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