Minimal thyroid ophthalmopathy

We studied six patients with the clinical, sonographic, CT, and biochemical profile of minimal euthyroid Graves' disease (MEGD). This syndrome was characterized clinically by small but obtrusive and measurable amounts of diplopia related to endocrine ophthalmopathy and the conspicuous absence of systemic or laboratory signs of thyrotoxicosis. Diagnostic emphasis will be given to certain manifestations of MEGD, namely the clinical patterns of ophthalmoparesis, the results of forced duction testing, orbital ultrasonography, and CT, as well as the need to obtain, in some cases, special antibody studies and the thyrotropin releasing hormone stimulation test.