Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Polytene Chromosomes02:04

Polytene Chromosomes

10.9K
Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also...
10.9K
Chromosome Structure02:40

Chromosome Structure

26.0K
A functional eukaryotic chromosome must contain three elements: a centromere, telomeres, and numerous origins of replication.
The centromere is a DNA sequence that links sister chromatids. This is also where kinetochores, protein complexes to which spindle microtubules attach, are constructed after the chromosome is replicated. The kinetochores allow the spindle microtubules to move the chromosomes within the cell during cell division.
Telomeres consist of non-coding repetitive nucleotide...
26.0K
Chromosome Structure02:40

Chromosome Structure

6.2K
6.2K
Chromosome Replication02:31

Chromosome Replication

10.5K
Before a cell can divide, it must accurately replicate all of its chromosomes, including the DNA and its associated histone and non-histone proteins.  This process begins at numerous origins of replication during the S phase of the cell cycle in each of a cell’s chromosomes simultaneously. Certain nucleotides can act as origins of replication, but these sequences are not well defined - especially in complex, multi-cellular, eukaryotic species. The length of DNA that spans an origin...
10.5K
Lampbrush Chromosomes01:51

Lampbrush Chromosomes

8.6K
In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops...
8.6K
Microtubule Instability02:17

Microtubule Instability

6.1K
Microtubules are hollow cylindrical filaments having a diameter of approximately 25 nm and a length that varies from 200 nm to 25 μm. GTP-bound tubulin subunits form αβ-heterodimers for microtubule assembly. These core building blocks interact longitudinally, polymerizing into protofilaments. The protofilaments then interact with one another through lateral bonding forces to form stable cylindrical microtubules. These cylindrical filaments are dynamic as they undergo repeated...
6.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The menstrual cycle through the lens of a wearable device: insights into physiology, sleep, and cycle variability.

NPJ digital medicine·2026
Same author

Decoding menstrual health across the lifespan: a scoping review of digital health tools in research.

medRxiv : the preprint server for health sciences·2026
Same author

Chromosomal instability and genomic alterations in cholangiocarcinoma from Northeastern Thailand.

The Journal of pathology·2025
Same author

A high-resolution, nanopore-based artificial intelligence assay for DNA replication stress in human cancer cells.

Nature communications·2025
Same author

In <i>E. coli</i> , the expression of mechanosensitive channels depends on environmental conditions.

microPublication biology·2025
Same author

A call to action for deciphering genetic variants in human pluripotent stem cells for cell therapy.

Cell stem cell·2025

Related Experiment Video

Updated: Jan 23, 2026

Chromosome Preparation From Cultured Cells
07:42

Chromosome Preparation From Cultured Cells

Published on: January 28, 2014

83.8K

Watching cancer cells evolve through chromosomal instability

Sarah C Johnson, Sarah E McClelland

    Nature
    |June 12, 2019
    PubMed
    Summary

    No abstract available in PubMed .

    Keywords:
    CancerCell biology

    More Related Videos

    Live Imaging to Study Microtubule Dynamic Instability in Taxane-resistant Breast Cancers
    06:02

    Live Imaging to Study Microtubule Dynamic Instability in Taxane-resistant Breast Cancers

    Published on: February 20, 2017

    7.9K
    Live Cell Imaging of Chromosome Segregation During Mitosis
    06:39

    Live Cell Imaging of Chromosome Segregation During Mitosis

    Published on: March 14, 2018

    9.8K

    Related Experiment Videos

    Last Updated: Jan 23, 2026

    Chromosome Preparation From Cultured Cells
    07:42

    Chromosome Preparation From Cultured Cells

    Published on: January 28, 2014

    83.8K
    Live Imaging to Study Microtubule Dynamic Instability in Taxane-resistant Breast Cancers
    06:02

    Live Imaging to Study Microtubule Dynamic Instability in Taxane-resistant Breast Cancers

    Published on: February 20, 2017

    7.9K
    Live Cell Imaging of Chromosome Segregation During Mitosis
    06:39

    Live Cell Imaging of Chromosome Segregation During Mitosis

    Published on: March 14, 2018

    9.8K