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Updated: Jan 23, 2026

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
[Tratamiento conservador de la osteoartrosis de cadera con toxina botulínica tipo A]
Sofía Durán-Hernández1, Juan Francisco Soto-Rodríguez2, Jorge Allen-Bobadilla3
1Servicio de Medicina Física y Rehabilitación, Hospital General Tacuba, ISSSTE, Ciudad de México, México.
Introduction:
Osteoarthritis (OA) of the hip is a low-grade inflammatory disease of multiple etiology that has a limited conservative management and insufficiently explored. The application of botulinum toxin type A (BoNT-A) produces in the applied muscle a temporary, delimitable and reversible flaccid paralysis, which applicated in a strategic way achives to reduce mechanical stress and pain.
Objective:
To evaluate the effect on pain perception, functionality and rigidity and changes in flexibility, internal and external rotation, before and 90 days after the application of BoNT-A.
Methods:
Clinical, experimental, longitudinal, open study, with a total of 35 patients and 45 hips treated. BoNT-A of 500 U was applied in iliac, adductor brevis and longus muscles.
Results:
The Wilcoxon test was used to compare the evaluation scores on days 0-90, observing the decrease in referred pain (p < 0.0001), rigidity (p < 0.002), improved perceived function (p < 0.001) and mobility arcs: flexion, internal and external rotation (p < 0.0001).
Conclusions:
The treatment with BoNT-A provides a conservative and safe option for the management of symptoms and physical restraint caused by hip OA.
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