Dyslipidemia Associated with Hypertension Increases the Risks for Coronary Heart Disease: A Case-Control Study in...

Area of Science:

• Cardiology
• Public Health
• Epidemiology

Background:

• Coronary Heart Disease (CHD) is the leading cause of death in Indonesia, accounting for 26.4% of all deaths.
• CHD mortality rates are four times higher than cancer mortality rates in Indonesia.
• Cardiovascular diseases represent a significant public health challenge.

Purpose of the Study:

• To investigate the association between dyslipidemia and hypertension in the incidence of Coronary Heart Disease (CHD).
• To determine if dyslipidemia, in conjunction with hypertension, elevates CHD risk.
• To analyze CHD risk factors at Harapan Kita Hospital, National Cardiovascular Center, Jakarta.

Main Methods:

• Case-control study design.
• Involved 163 participants: 82 in the CHD case group and 81 in the control group.
• Data analyzed using logistic regression, controlling for age.

Main Results:

• Dyslipidemia was present in 50% of the CHD group versus 17.3% in the control group.
• Hypertensive respondents with dyslipidemia had an 18.1 times higher likelihood of developing CHD compared to non-dyslipidemic individuals.
• Non-hypertensive respondents with dyslipidemia had a 2.5 times higher likelihood of developing CHD compared to non-dyslipidemic individuals.

Conclusions:

• Dyslipidemia is a significant risk factor for CHD, with its impact amplified by the presence of hypertension.
• The study highlights the critical role of managing both lipid profiles and blood pressure for CHD prevention.
• Regular medical checkups and lifestyle modifications are recommended for the general population.