Related Experiment Video
Updated: Jan 23, 2026
05:16
Sleeve Gastrectomy in Mice using Surgical Clips
Published on: November 14, 2020
7.3K
Laparoscopic Sleeve Gastrectomy in Sickle Cell Disease: a Case Series
Jin Han1,2,3, Michel Gowhari2, Victor R Gordeuk2
1Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA.
Obesity Surgery
|June 12, 2019
Summary
Bariatric surgery is a viable option for obese sickle cell patients, showing significant weight loss and improved health markers. This study found laparoscopic sleeve gastrectomy safe and effective in a small group of patients.
Area of Science:
- Metabolic Surgery
- Hematology
- Obesity Medicine
Background:
- Increasing prevalence of obesity in sickle cell disease (SCD) patients due to improved care.
- Limited data on the safety and efficacy of bariatric surgery in this population.
- Need for effective weight management strategies in SCD.
Observation:
- Four adult patients with mild sickle cell genotypes underwent laparoscopic sleeve gastrectomy.
- Patients experienced significant excess weight loss, ranging from 56% to 68%.
- No short-term or long-term surgical complications were reported.
Findings:
- Laparoscopic sleeve gastrectomy led to marked weight reduction in obese SCD patients.
- Associated with a decrease in white blood cell counts.
- Resulted in lower random glucose concentrations post-surgery.
Implications:
- Bariatric surgery appears to be a feasible and safe weight-loss intervention for select SCD patients.
- Suggests potential benefits beyond weight loss, such as improved inflammatory markers.
- Highlights the need for further research into surgical weight management for sickle cell disease.
Related Concept Videos
01:10Resistors In Series
6.1K
A resistor is an ohmic device that limits the flow of charge in a circuit. Most circuits have more than one resistor. If several resistors are connected together and connected to a battery, the current supplied by the battery depends on the equivalent resistance of the circuit. The equivalent resistance of a combination of resistors depends on both their individual values and how they are connected. The simplest combination of resistors is the series combination.
In a series circuit, the...
In a series circuit, the...
6.1K
01:17Series Resonance
777
The RLC circuit impedance is defined as the ratio of the supply voltage to the circuit current. Resonance in such a circuit occurs when the imaginary part of this impedance equals zero. This specific condition means that the inductive reactance is exactly equal to the capacitive reactance. The frequency at which this happens is known as the resonant frequency. Mathematically, the resonant frequency is inversely proportional to the square root of the product of the inductance (L) and capacitance...
777
01:17Trigonometric Fourier series
770
Fourier series is a foundational mathematical technique that decomposes periodic functions into an infinite series of sinusoidal harmonics. This method enables the representation of complex periodic signals as sums of simple sine and cosine functions, facilitating their analysis and interpretation in various fields, including signal processing, acoustics, and electrical engineering.
The trigonometric Fourier series specifically expresses a periodic function with a defined period T using sine...
The trigonometric Fourier series specifically expresses a periodic function with a defined period T using sine...
770
01:21Convergence of Fourier Series
386
The Fourier series is a powerful mathematical tool for representing periodic signals as an infinite sum of complex exponentials. In practice, this infinite series is truncated to a finite number of terms, yielding a partial sum. This truncation makes the approximation of the signal feasible but introduces certain challenges, particularly near discontinuities, known as the Gibbs phenomenon.
The Gibbs phenomenon refers to the persistent oscillations and overshoots that occur near discontinuities...
The Gibbs phenomenon refers to the persistent oscillations and overshoots that occur near discontinuities...
386
01:22Series R—L Circuit Transients
386
In a series resistor-inductor (R-L) circuit, closing the switch at the start of the time period simulates a three-phase short circuit, a fault condition where all three phases of an unloaded synchronous machine are short-circuited. When there is no fault impedance and no initial current, the initial voltage is determined by the phase angle of the source voltage.
Using Kirchhoff's Voltage Law (KVL) to analyze this circuit helps determine the total asymmetrical fault current, which consists...
Using Kirchhoff's Voltage Law (KVL) to analyze this circuit helps determine the total asymmetrical fault current, which consists...
386
01:14Series and Parallel Capacitors
9.1K
Capacitors, fundamental components in electronic circuits, can be connected in series and/or parallel configurations. Each configuration has different impacts on the overall behavior of the circuit.
First, consider capacitors connected in series to a battery. In this configuration, the plate connected to the battery's positive terminal develops a positive charge, while the plate attached to the negative terminal becomes negatively charged. An equal magnitude of charge is induced on the...
First, consider capacitors connected in series to a battery. In this configuration, the plate connected to the battery's positive terminal develops a positive charge, while the plate attached to the negative terminal becomes negatively charged. An equal magnitude of charge is induced on the...
9.1K