ASSOCIATION OF BONE MINERAL DENSITY WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN POSTMENOPAUSAL WOMEN

Area of Science:

• Pulmonary Medicine
• Endocrinology
• Geriatrics

Background:

• Osteoporosis (OP) is prevalent in chronic obstructive pulmonary disease (COPD) patients.
• Research on OP and COPD is limited in postmenopausal women.

Purpose of the Study:

• To investigate the association between bone mineral density (BMD) and COPD in postmenopausal women.

Main Methods:

• Cross-sectional study of 133 female ex-smokers with COPD and 31 controls.
• BMD measured using dual-energy X-ray absorptiometry.
• Analysis of groups based on airway obstruction severity.

Main Results:

• COPD patients exhibited lower T-scores and higher osteopenia/OP prevalence than controls.
• Airway obstruction severity correlated significantly with T-scores in COPD patients.
• COPD independently predicted increased osteopenia/OP risk in postmenopausal women.

Conclusions:

• COPD and airway obstruction severity are strongly linked to BMD.
• Postmenopausal women with COPD face elevated osteopenia and OP risk.
• Severe airway obstruction exacerbates osteopenia/OP risk in COPD patients.