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Five-year readmission and mortality differ by ischemic stroke subtype.

Anna Therese Bjerkreim1, Andrej Netland Khanevski2, Lars Thomassen1

  • 1Department of Clinical Medicine, University of Bergen, Norway; Department of Neurology, Haukeland University Hospital, Norway.

Journal of the Neurological Sciences
|June 12, 2019
PubMed
Summary
This summary is machine-generated.

Stroke subtype significantly impacts readmission and mortality risk. Cardioembolism (CE) stroke patients face higher risks, while small vessel occlusion (SVO) stroke patients have the lowest risks within five years.

Keywords:
Ischemic strokeIschemic stroke subtypeMortalityReadmissionTransient ischemic attack

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Area of Science:

  • Neurology
  • Cardiology
  • Public Health

Background:

  • Ischemic stroke (IS) and transient ischemic attack (TIA) subtypes influence patient outcomes.
  • Understanding subtype-specific risks for readmission and mortality is crucial for patient management.

Purpose of the Study:

  • To investigate the five-year incidence and risk of all-cause readmission, cause-specific readmission, and mortality after IS or TIA, stratified by stroke subtype.

Main Methods:

  • Retrospective review of 1453 IS/TIA patients (2007-2012).
  • Stroke etiology classified into large-artery atherosclerosis (LAA), cardioembolism (CE), small vessel occlusion (SVO), stroke of other determined etiology (SOE), multiple etiologies (ME), or cryptogenic stroke (CS).
  • Kaplan-Meier and Cox regression analyses used to assess readmission and mortality risks.

Main Results:

  • Five-year all-cause readmission incidence was 72.6%, with infections, cardiac disease, stroke, and fractures as common causes.
  • Small vessel occlusion (SVO) patients had a 21% lower risk of readmission and 48% lower risk of death compared to other subtypes.
  • Cardioembolism (CE) patients showed a 25% higher risk of readmission and 34% higher risk of death; CE also had a 75% higher risk of cardiac readmission.

Conclusions:

  • Significant variation in five-year readmission and mortality rates exists among IS/TIA subtypes.
  • Cardioembolism (CE) subtype is associated with the highest risk of readmission and death.
  • Small vessel occlusion (SVO) subtype demonstrates the lowest risk of readmission and death.