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Updated: Aug 18, 2026

Generation of Subcutaneous and Intrahepatic Human Hepatocellular Carcinoma Xenografts in Immunodeficient Mice
Published on: September 25, 2013
Chemotherapy of human non-Hodgkin lymphoma (NHL) xenografts
L Kopper1, P Nagy, E Magyarosy
11st Institute of Pathology and Experimental Cancer Research, Semmelweis Medical University, Budapest, Hungary.
Abstract:
Three human NHL (B-cell type) were established successfully as serially transplantable xenografts in artificially immunesuppressed CBA mice. All of them preserved the phenotypic characteristics of the original tumour even after several passages. The transplanted tumours were highly sensitive to cyclophosphamide and methotrexate, reflecting the results obtained in clinical practice, and relatively sensitive to dianhydrogalactitol.
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