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Attention deficit hyperactivity disorder (ADHD) in children with epilepsy
Man Wang1, Qin Zhao1, Huicong Kang1
1Department of Neurology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jie Fang Avenue, Wuhan, 430030, China.
Children with epilepsy show higher rates of Attention Deficit Hyperactivity Disorder (ADHD). ADHD in epilepsy is linked to factors like age, seizure frequency, and antiepileptic drug use.
Area of Science:
- Pediatric Neurology
- Child Psychiatry
Background:
- Attention Deficit Hyperactivity Disorder (ADHD) is a frequent comorbidity in childhood epilepsy.
- While studied in Western countries, research on ADHD in Chinese children with epilepsy is limited.
Purpose of the Study:
- To determine the incidence rate of ADHD in Chinese children with epilepsy.
- To analyze the relationship between epilepsy and ADHD in this population.
Main Methods:
- A study involving 206 children (aged 6-16) with epilepsy and 58 healthy controls.
- Utilized assessment instruments including DSM-IV ADHD criteria, ADHD Rating Scale-IV, and SNAP-IV Rating Scale.
Main Results:
- The prevalence of ADHD was significantly higher in children with epilepsy (24.76%) compared to controls (5.17%).
- ADHD in epilepsy was associated with younger age, early onset, and frequent seizures. Higher comorbidity rates were observed with antiepileptic drug (AED) use, particularly multiple AEDs and traditional AEDs.
Conclusions:
- Children with epilepsy exhibit more attention problems than healthy peers.
- ADHD in childhood epilepsy is associated with male sex, younger age, early onset, seizure frequency, and polytherapy with AEDs.
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