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Updated: Jan 23, 2026

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Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
Published on: June 13, 2018
11.2K
Overview of Deep Dermal Fillers
Michael H Liu1, David P Beynet1,2, Nima M Gharavi3
1Department of Dermatology, University of California Los Angeles, Los Angeles, California.
Facial Plastic Surgery : FPS
|June 13, 2019
Summary
This review explores semipermanent and permanent dermal fillers for facial aging correction. Understanding these long-lasting options is crucial for safe and effective soft tissue augmentation in cosmetic dermatology.
Area of Science:
- Dermatology
- Cosmetic Surgery
- Aesthetic Medicine
Background:
- Dermal fillers are integral to cosmetic dermatology, shifting focus to soft tissue augmentation for facial aging.
- Nine new dermal fillers approved by the U.S. Food and Drug Administration in the past 5 years highlight increased usage.
- Dermal fillers are categorized into temporary, semipermanent, and permanent types, with varying durations of effect.
Purpose of the Study:
- To review semipermanent and permanent injectable dermal fillers for soft tissue augmentation.
- To emphasize the importance of clinician understanding of these durable fillers for patient counseling and procedure execution.
Main Methods:
- Literature review focusing on semipermanent (poly-L-lactic acid, calcium hydroxylapatite) and permanent (polymethylmethacrylate, liquid silicone) dermal fillers.
- Analysis of dermal filler types, safety, efficacy, and adverse event potential.
Main Results:
- Temporary fillers (e.g., hyaluronic acid) offer limited duration (1-2 years).
- Semipermanent and permanent fillers provide durable correction for the aging face.
- Extended duration of semipermanent and permanent fillers necessitates awareness of potential adverse events.
Conclusions:
- Semipermanent and permanent dermal fillers are valuable tools for facial rejuvenation.
- Thorough clinician knowledge of these deep dermal fillers is essential for optimal patient outcomes and safety.
- Effective counseling and recommendation require a deep understanding of filler properties and risks.
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